Concepedia

Study Design Optimization

Study Design Optimization is a methodological framework in population toxicokinetics that specifies the systematic refinement of experimental and observational study parameters to maximize statistical power, minimize bias, and enhance the precision of exposure-response inferences while accounting for inter-individual variability and study constraints.

72

Publications

3.7K

Citations

272

Authors

165

Institutions

Publications per year

2017–2026

24

Parents

Publications

72

Immigration and Crime: Assessing a Contentious Issue

Graham C. Ousey, Charis E. Kubrin · Annual Review of Criminology · 2017 · 365 citations · Full text

, , +13

Optimal design in random-effects regression models

France Mentré · Biometrika · 1997 · 269 citations

, , +15

Incorporating Toxicity Considerations Into the Design of Two-Stage Phase II Clinical Trials

John Bryant, Roger Day · Biometrics · 1995 · 261 citations

, , +14

Confidence Intervals and Power Calculations for Within-Person Biological Variation: Effect of Analytical Imprecision, Number of Replicates, Number of Samples, and Number of Individuals

Thomas Røraas, Per Hyltoft Petersen, Sverre Sandberg · Clinical Chemistry · 2012 · 133 citations · Full text

, , +12

Design optimization study of the extraction of olive leaves performed with pressurized liquid extraction using response surface methodology

Nikos Xynos, Georgios Papaefstathiou, Evagelos Gikas et al. · Separation and Purification Technology · 2013 · 116 citations

, , +11

1–5 of 72

Authors

272

  1. FM
    France Mentré

    Inserm, France

    2 publications · 341 citations

    2

    h-index

  2. JB
    John Bryant

    University of Pittsburgh, United States

    1 publications · 261 citations

    1

    h-index

  3. KK
    Kristin Karlsson

    Medical Products Agency, Sweden

    1 publications · 68 citations

    1

    h-index

  4. VG
    Vahid Ghasemzadeh‐Mohammadi

    National Nutrition and Food Technology Research Institute, Iran

    1 publications · 32 citations

    1

    h-index

  5. BA
    Ben Armstrong

    London School of Hygiene & Tropical Medicine, United Kingdom

    1 publications · 34 citations

    1

    h-index

1–5 of 272

Institutions

165

  1. Inserm

    Paris, France

    4 h-index

    7 publications

    647 citations

  2. Case Western Reserve University

    Cleveland, United States

    3 h-index

    6 publications

    297 citations

  3. St George's, University of London

    London, United Kingdom

    2 h-index

    7 publications

    205 citations

  4. Université Paris Cité

    Paris, France

    2 h-index

    5 publications

    361 citations

  5. Assistance Publique – Hôpitaux de Paris

    Paris, France

    2 h-index

    5 publications

    361 citations

  6. Medical Research Council

    London, United Kingdom

    2 h-index

    3 publications

    171 citations

  7. Sahand University of Technology

    Tabriz, Iran

    2 h-index

    4 publications

    87 citations

  8. Johns Hopkins Medicine

    Baltimore, United States

    1 h-index

    1 publications

    14 citations

1–8 of 165

Venues

  1. Biometrics

    4 publications · 407 citations

    4

    h-index

  2. Fuel

    2 publications · 66 citations

    2

    h-index

  3. Archives of Toxicology

    2 publications · 77 citations

    2

    h-index

  4. Statistical Methods in Medical Research

    2 publications · 28 citations

    2

    h-index

  5. Biometrika

    2 publications · 298 citations

    2

    h-index

1–5