Concepedia

Structural Basis Of Capsid Destabilization

Structural Basis of Capsid Destabilization is a molecular virology concept that identifies the specific conformational changes and intermolecular interactions within the viral capsid that facilitate its disassembly during cell entry, distinguishing it from broader mechanisms of viral uncoating by focusing on the atomic-level architecture governing capsid instability.

56

Publications

2.5K

Citations

250

Authors

112

Institutions

Publications per year

2017–2026

14

Parents

Publications

56

Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site

Chuang Liu, Juan R. Perilla, Jiying Ning et al. · Nature Communications · 2016 · 159 citations · Full text

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Disulfide Bond Stabilization of the Hexameric Capsomer of Human Immunodeficiency Virus

Owen Pornillos, Barbie K. Ganser‐Pornillos, Banumathi Sankaran et al. · Journal of Molecular Biology · 2010 · 142 citations · Full text

, , +16

Destabilization of the HIV-1 Complementary Sequence of TAR by the Nucleocapsid Protein Through Activation of Conformational Fluctuations

Joel Azoulay, Jean-Pierre Clamme, Jean-Luc Darlix et al. · Journal of Molecular Biology · 2003 · 117 citations

, , +16

Atomic structure of the human cytomegalovirus capsid with its securing tegument layer of pp150

Xuekui Yu, Jonathan Jih, Jiansen Jiang et al. · Science · 2017 · 116 citations · Full text

, , +16

Structure of human enterovirus 71 in complex with a capsid-binding inhibitor

Pavel Plevka, Rushika Perera, Moh Lan Yap et al. · Proceedings of the National Academy of Sciences · 2013 · 83 citations · Full text

, , +17

1–5 of 56

Authors

250

  1. CA
    Christopher Aiken

    Vanderbilt University, United States

    4 publications · 296 citations

    4

    h-index

  2. JR
    José R. Castón

    Centro Nacional de Biotecnología, Spain

    3 publications · 171 citations

    3

    h-index

  3. PE
    Peter E. Prevelige

    University of Alabama at Birmingham, United States

    3 publications · 249 citations

    3

    h-index

  4. XY
    Xuekui Yu

    University of California, Los Angeles, United States

    2 publications · 130 citations

    2

    h-index

  5. PP
    Pedro Pablo

    Universidad Autónoma de Madrid, Spain

    2 publications · 94 citations

    2

    h-index

1–5 of 250

Institutions

112

  1. Universidad Autónoma de Madrid

    Madrid, Spain

    4 h-index

    11 publications

    443 citations

  2. Scripps Research Institute

    San Diego, United States

    4 h-index

    10 publications

    774 citations

  3. Centro Nacional de Biotecnología

    Madrid, Spain

    4 h-index

    13 publications

    512 citations

  4. Vanderbilt University

    Nashville, United States

    3 h-index

    7 publications

    535 citations

  5. Vanderbilt University Medical Center

    Nashville, United States

    3 h-index

    7 publications

    244 citations

  6. Pennsylvania State University

    State College, United States

    3 h-index

    11 publications

    377 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    8 publications

    444 citations

  8. Purdue University West Lafayette

    West Lafayette, United States

    3 h-index

    12 publications

    788 citations

1–8 of 112

Venues

  1. Journal of Virology

    JVI · 9 publications · 299 citations

    9

    h-index

  2. Journal of Molecular Biology

    JMB · 8 publications · 522 citations

    8

    h-index

  3. Virology

    7 publications · 244 citations

    7

    h-index

  4. Retrovirology

    3 publications · 172 citations

    3

    h-index

  5. PLoS Pathogens

    2 publications · 78 citations

    2

    h-index

1–5