Concepedia

Strand-displacement Replication

Strand-Displacement Replication is a mechanism of nucleic acid synthesis in which an advancing replication fork continuously elongates a nascent DNA or RNA strand while displacing the complementary parental strand without immediate degradation or nicking, distinguishing it from replication models requiring discontinuous strand cleavage or replacement.

44

Publications

2.3K

Citations

149

Authors

69

Institutions

Publications per year

2017–2026

6

Parents

Publications

44

Bacteriophage T4 gene 41 protein, required for the synthesis of RNA primers, is also a DNA helicase.

Malabi M. Venkatesan, Lynn L. Silver, Nancy G. Nossal · Journal of Biological Chemistry · 1982 · 190 citations · Full text

, , +14

Parvoviruses: Small Does Not Mean Simple

Susan F. Cotmore, Peter Tattersall · Annual Review of Virology · 2014 · 178 citations · Full text

, , +17

Replication of Mitochondrial DNA in Mouse L Cells and Their Thymidine Kinase <sup>-</sup> Derivatives: Displacement Replication on a Covalently-Closed Circular Template

Donald L. Robberson, David A. Clayton · Proceedings of the National Academy of Sciences · 1972 · 135 citations · Full text

, , +13

Discovery of a Major D-Loop Replication Origin Reveals Two Modes of Human mtDNA Synthesis

Jennifer L. Fish, Nicola Raule, Giuseppe Attardi · Science · 2004 · 127 citations

, , +17

Helix-destabilizing Activity of φ29 Single-stranded DNA Binding Protein: Effect on the Elongation Rate During Strand Displacement DNA Replication

Marı́a S. Soengas, Crisanto Gutiérrez, Margarita Salas · Journal of Molecular Biology · 1995 · 90 citations

, , +17

1–5 of 44

Authors

149

  1. MS
    Margarita Salas

    Centro de Biología Molecular Severo Ochoa, Spain

    4 publications · 152 citations

    4

    h-index

  2. SD
    Stephen D. Bell

    Hutchison/MRC Research Centre, United Kingdom

    3 publications · 64 citations

    3

    h-index

  3. CG
    Crisanto Gutiérrez

    Centro de Biología Molecular Severo Ochoa, Spain

    3 publications · 112 citations

    3

    h-index

  4. DA
    David A. Clayton

    Stanford University, United States

    3 publications · 187 citations

    3

    h-index

  5. MS
    Marı́a S. Soengas

    Spanish National Cancer Research Centre, Spain

    3 publications · 112 citations

    3

    h-index

1–5 of 149

Institutions

69

  1. Universidad Autónoma de Madrid

    Madrid, Spain

    5 h-index

    16 publications

    664 citations

  2. Centro de Biología Molecular Severo Ochoa

    Madrid, Spain

    5 h-index

    15 publications

    624 citations

  3. Stanford University

    Stanford, United States

    3 h-index

    8 publications

    522 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    8 publications

    454 citations

  5. Consejo Superior de Investigaciones Científicas

    Madrid, Spain

    3 h-index

    6 publications

    230 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    10 publications

    579 citations

  7. Instituto de Química Física Blas Cabrera

    Madrid, Spain

    2 h-index

    4 publications

    44 citations

  8. University of Rochester

    Rochester, United States

    2 h-index

    8 publications

    362 citations

1–8 of 69

Venues

  1. Journal of Biological Chemistry

    JBC · 10 publications · 518 citations

    10

    h-index

  2. Nucleic Acids Research

    7 publications · 295 citations

    7

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 326 citations

    5

    h-index

  4. Journal of Molecular Biology

    JMB · 2 publications · 134 citations

    2

    h-index

  5. Journal of Virology

    JVI · 2 publications · 111 citations

    2

    h-index

1–5