Concepedia

Steroid Dehydrogenation

Steroid Dehydrogenation is a biochemical reaction process in steroid catabolism whereby a steroid molecule undergoes the removal of hydrogen atoms to form double bonds, mediated by specific dehydrogenase enzymes that catalyze redox transformations at defined carbon positions within the steroid nucleus or side chain.

187

Publications

7.2K

Citations

613

Authors

182

Institutions

Publications per year

2017–2026

13

Parents

Publications

187

Microbial conversion of steroid compounds: recent developments

Pedro Fernandes, Alexandra Cruz, B. Angelova et al. · Enzyme and Microbial Technology · 2003 · 546 citations

, , +16

Early history of steroid chemistry in Mexico: the story of three remarkable men

Pedro A. Lehmann F. · Steroids · 1992 · 412 citations

, , +16

Human 3β-Hydroxysteroid Dehydrogenase/ δ5→4Isomerase from Placenta: Expression in Nonsteroidogenic Cells of a Protein that Catalyzes the Dehydrogenation/Isomerization of C21 and C19 Steroids*

Matthew C. Lorence, Barbara A. Murry, John M. Trant et al. · Endocrinology · 1990 · 213 citations

, , +17

OXIDATION OF STEROIDS BY MICRO ÖRGANISMS. III. SIDE CHAIN DEGRADATION, RING D-CLEAVAGE AND DEHYDROGENATION IN RING A

Josef Fried, Richard W. Thoma, Anna Klingsberg · Journal of the American Chemical Society · 1953 · 174 citations

, , +14

11 beta-Hydroxysteroid dehydrogenase in cultured hippocampal cells reactivates inert 11-dehydrocorticosterone, potentiating neurotoxicity

Vigna Rajan, C R Edwards, JR Seckl · Journal of Neuroscience · 1996 · 172 citations · Full text

, , +17

1–5 of 187

Authors

613

  1. AW
    A. Wettstein

    Novartis (Switzerland), Switzerland

    6 publications · 215 citations

    6

    h-index

  2. HP
    H.M. Pinheiro

    Instituto Superior Técnico, Portugal

    5 publications · 616 citations

    5

    h-index

  3. JM
    Joaquim M. S. Cabral

    Instituto Superior Técnico, Portugal

    5 publications · 616 citations

    5

    h-index

  4. HJ
    Howard J. Ringold

    Syntek Technologies (United States), United States

    5 publications · 188 citations

    5

    h-index

  5. KH
    K. Heusler

    Novartis (Switzerland), Switzerland

    4 publications · 88 citations

    4

    h-index

1–5 of 613

Institutions

182

  1. Novartis (Switzerland)

    Basel, Switzerland

    7 h-index

    21 publications

    703 citations

  2. Chinese Academy of Sciences

    Beijing, China

    6 h-index

    23 publications

    535 citations

  3. Instituto Superior Técnico

    Lisbon, Portugal

    5 h-index

    17 publications

    2.9K citations

  4. Tianjin University of Science and Technology

    Tianjin, China

    3 h-index

    17 publications

    428 citations

  5. Instituto Politécnico de Lisboa

    Lisbon, Portugal

    3 h-index

    10 publications

    188 citations

  6. Lund University

    Lund, Sweden

    3 h-index

    6 publications

    575 citations

  7. Wrocław University of Environmental and Life Sciences

    Wroclaw, Poland

    3 h-index

    5 publications

    154 citations

  8. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    11 publications

    430 citations

1–8 of 182

Venues

  1. Tetrahedron

    10 publications · 214 citations

    10

    h-index

  2. Steroids

    10 publications · 647 citations

    10

    h-index

  3. Journal of Biological Chemistry

    JBC · 8 publications · 288 citations

    8

    h-index

  4. Helvetica Chimica Acta

    8 publications · 244 citations

    8

    h-index

  5. Biotechnology and Bioengineering

    7 publications · 335 citations

    7

    h-index

1–5