Concepedia

Steric Modulation Of Selectivity

Steric Modulation of Selectivity is a bioisosteric design strategy that belongs to the class of molecular optimization techniques, distinguished by its deliberate alteration of non-covalent binding interactions through spatially controlled substituent placement to enhance target specificity.

63

Publications

2.8K

Citations

289

Authors

100

Institutions

Publications per year

2017–2026

8

Parents

Publications

63

Three-Dimensional Correlation of Steric and Electronic Free Energy Relationships Guides Asymmetric Propargylation

Kaid C. Harper, Matthew S. Sigman · Science · 2011 · 213 citations

, , +15

Systematic Variation of Bidentate Ligands Used in Aryl Halide Amination. Unexpected Effects of Steric, Electronic, and Geometric Perturbations

Blake C. Hamann, John F. Hartwig · Journal of the American Chemical Society · 1998 · 188 citations

, , +14

Selective Intermolecular Amination of CH Bonds at Tertiary Carbon Centers

Jennifer L. Roizen, David N. Zalatan, J. Du Bois · Angewandte Chemie International Edition · 2013 · 146 citations

, , +9

Steric Selectivity in Na Channels Arising from Protein Polarization and Mobile Side Chains

Dezső Boda, Wolfgang Nonner, Mónika Valiskó et al. · Biophysical Journal · 2007 · 142 citations · Full text

, , +17

Controlling Oxygen Reduction Selectivity through Steric Effects: Electrocatalytic Two‐Electron and Four‐Electron Oxygen Reduction with Cobalt Porphyrin Atropisomers

Bin Lv, Xialiang Li, Kai Guo et al. · Angewandte Chemie International Edition · 2021 · 142 citations

, , +14

1–5 of 63

Authors

289

  1. QZ
    Qingxin Zhang

    Hebei University of Technology, China

    2 publications · 154 citations

    2

    h-index

  2. XL
    Xialiang Li

    Shaanxi Normal University, China

    2 publications · 154 citations

    2

    h-index

  3. YX
    Yujie Xiong

    University of Science and Technology of China, China

    2 publications · 154 citations

    2

    h-index

  4. BL
    Bin Lv

    Shaanxi Normal University, China

    2 publications · 154 citations

    2

    h-index

  5. UA
    Ulf‐Peter Apfel

    Ruhr University Bochum, Germany

    2 publications · 154 citations

    2

    h-index

1–5 of 289

Institutions

100

  1. Stanford University

    Stanford, United States

    3 h-index

    9 publications

    902 citations

  2. University of Science and Technology of China

    Hefei, China

    3 h-index

    9 publications

    693 citations

  3. Government of the Republic of Korea

    Seoul, South Korea

    3 h-index

    10 publications

    219 citations

  4. Duke University

    Durham, United States

    2 h-index

    2 publications

    186 citations

  5. Collaborative Innovation Center of Chemistry for Energy Materials

    Shanghai, China

    2 h-index

    6 publications

    462 citations

  6. Ruhr University Bochum

    Bochum, Germany

    2 h-index

    2 publications

    154 citations

  7. Chemical Synthesis Lab

    Singapore, Singapore

    2 h-index

    4 publications

    114 citations

  8. Fraunhofer Institute for Environmental, Safety and Energy Technology UMSICHT

    Oberhausen, Germany

    2 h-index

    2 publications

    154 citations

1–8 of 100

Venues

  1. Tetrahedron

    5 publications · 102 citations

    5

    h-index

  2. The Journal of Organic Chemistry

    JOC · 5 publications · 152 citations

    5

    h-index

  3. Journal of the American Chemical Society

    JACS · 5 publications · 419 citations

    5

    h-index

  4. Inorganic Chemistry

    4 publications · 255 citations

    4

    h-index

  5. Organic Letters

    OL · 4 publications · 108 citations

    4

    h-index

1–5