Concepedia

Spliceosome Dynamics

Spliceosome Dynamics is a theoretical framework that characterizes the temporally regulated assembly, conformational remodeling, and disassembly of the spliceosome complex during pre-mRNA splicing through the coordinated action of small nuclear RNAs and associated proteins.

129

Publications

9.6K

Citations

596

Authors

214

Institutions

Publications per year

2017–2026

32

Parents

Publications

129

Dynamic Protein-Protein Interaction Wiring of the Human Spliceosome

Anna Hegele, Atanas Kamburov, Chrysovalantis Sourlis et al. · Molecular Cell · 2012 · 431 citations · Full text

, , +13

Structure of a yeast spliceosome at 3.6-angstrom resolution

Chuangye Yan, Jing Hang, Ruixue Wan et al. · Science · 2015 · 344 citations

, , +17

PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome

Beate Schwer, Christine Guthrie · Nature · 1991 · 337 citations

, , +8

Ordered and Dynamic Assembly of Single Spliceosomes

Aaron A. Hoskins, Larry J. Friedman, Sarah S. Gallagher et al. · Science · 2011 · 292 citations · Full text

, , +17

Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex

David Haselbach, Ilya Komarov, Dmitry E. Agafonov et al. · Cell · 2018 · 219 citations · Full text

, , +14

1–5 of 129

Authors

596

  1. RL
    Reinhard Lührmann

    Max Planck Institute for Biophysical Chemistry, Germany

    11 publications · 1.4K citations

    11

    h-index

  2. AA
    Aaron A. Hoskins

    University of Wisconsin–Madison, United States

    7 publications · 576 citations

    7

    h-index

  3. MS
    Melissa S. Jurica

    University of California, Santa Cruz, United States

    6 publications · 493 citations

    6

    h-index

  4. MJ
    Melissa J. Moore

    Howard Hughes Medical Institute, United States

    6 publications · 664 citations

    6

    h-index

  5. JD
    Jean D. Beggs

    University of Edinburgh, United Kingdom

    5 publications · 499 citations

    5

    h-index

1–5 of 596

Institutions

214

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    13 h-index

    36 publications

    4.2K citations

  2. Max Planck Institute for Biophysical Chemistry

    Göttingen, Germany

    11 h-index

    54 publications

    7.6K citations

  3. University of California, San Francisco

    San Francisco, United States

    9 h-index

    29 publications

    2.8K citations

  4. Brandeis University

    Waltham, United States

    6 h-index

    22 publications

    2.9K citations

  5. University of California, Santa Cruz

    Santa Cruz, United States

    6 h-index

    17 publications

    823 citations

  6. University of Wisconsin–Madison

    Madison, United States

    6 h-index

    27 publications

    929 citations

  7. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    6 h-index

    20 publications

    919 citations

  8. University of California San Diego

    San Diego, United States

    5 h-index

    10 publications

    425 citations

1–8 of 214

Venues

  1. Nucleic Acids Research

    13 publications · 654 citations

    13

    h-index

  2. RNA

    11 publications · 634 citations

    11

    h-index

  3. Molecular Cell

    8 publications · 1.2K citations

    8

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 600 citations

    8

    h-index

  5. Cell

    6 publications · 647 citations

    6

    h-index

1–5