Concepedia

Spirocyclization-based Probes

Spirocyclization-Based Probes is a class of fluorogenic bioorth Crushergon probes that generate fluorescence through a ring-opening reaction initiated by a bioorthogonal ligation, wherein the quenching spirocyclic structure is selectively cleaved to release a fluorescent reporter.

31

Publications

2.5K

Citations

185

Authors

51

Institutions

Publications per year

2017–2026

14

Parents

Publications

31

Development of a Highly Specific Rhodamine-Based Fluorescence Probe for Hypochlorous Acid and Its Application to Real-Time Imaging of Phagocytosis

Suguru Kenmoku, Yasuteru Urano, Hirotatsu Kojima et al. · Journal of the American Chemical Society · 2007 · 463 citations

, , +17

A dual emission fluorescent probe enables simultaneous detection of glutathione and cysteine/homocysteine

Xiao‐Feng Yang, Qian Huang, Yaogang Zhong et al. · Chemical Science · 2014 · 341 citations · Full text

, , +17

Rational Design of Highly Sensitive Fluorescence Probes for Protease and Glycosidase Based on Precisely Controlled Spirocyclization

Masayo Sakabe, Daisuke Asanuma, Mako Kamiya et al. · Journal of the American Chemical Society · 2012 · 260 citations

, , +16

Native Chemical Ligation Combined with Spirocyclization of Benzopyrylium Dyes for the Ratiometric and Selective Fluorescence Detection of Cysteine and Homocysteine

Hongmin Lv, Xiao‐Feng Yang, Yaogang Zhong et al. · Analytical Chemistry · 2014 · 153 citations

, , +17

Bioimaging Probes for Reactive Oxygen Species and Reactive Nitrogen Species

Tetsuo Nagano · Journal of Clinical Biochemistry and Nutrition · 2009 · 143 citations · Full text

, , +17

1–5 of 31

Authors

185

  1. YU
    Yasuteru Urano

    The University of Tokyo, Japan

    8 publications · 1.1K citations

    8

    h-index

  2. MK
    Mako Kamiya

    The University of Tokyo, Japan

    6 publications · 533 citations

    6

    h-index

  3. XY
    Xiao‐Feng Yang

    Northwest University, China

    5 publications · 615 citations

    5

    h-index

  4. TN
    Tetsuo Nagano

    The University of Tokyo, Japan

    4 publications · 936 citations

    4

    h-index

  5. RJ
    Ryu J. Iwatate

    The University of Tokyo, Japan

    3 publications · 400 citations

    3

    h-index

1–5 of 185

Institutions

51

  1. The University of Tokyo

    Tokyo, Japan

    9 h-index

    41 publications

    5.5K citations

  2. Japan Science and Technology Agency

    Tokyo, Japan

    7 h-index

    18 publications

    2.1K citations

  3. Northwest University

    Xi'an, China

    5 h-index

    26 publications

    3.2K citations

  4. Japan Agency for Medical Research and Development

    Tokyo, Japan

    5 h-index

    10 publications

    683 citations

  5. Ministry of Education of the People's Republic of China

    Beijing, China

    4 h-index

    16 publications

    1.8K citations

  6. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    7 publications

    492 citations

  7. Dalian Institute of Chemical Physics

    Dalian, China

    2 h-index

    6 publications

    466 citations

  8. University of Münster

    Münster, Germany

    2 h-index

    8 publications

    172 citations

1–8 of 51

Venues

  1. Journal of the American Chemical Society

    JACS · 4 publications · 815 citations

    4

    h-index

  2. Analytical Chemistry

    4 publications · 309 citations

    4

    h-index

  3. Bioorganic & Medicinal Chemistry

    3 publications · 113 citations

    3

    h-index

  4. Bioorganic & Medicinal Chemistry Letters

    2 publications · 74 citations

    2

    h-index

  5. Sensors and Actuators B Chemical

    2 publications · 46 citations

    2

    h-index

1–5