Concepedia

Spindle Assembly Checkpoint Defects

Spindle Assembly Checkpoint Defects is a biological phenomenon characterized by the failure of the mitotic surveillance mechanism that normally ensures proper chromosome segregation by delaying anaphase onset until all kinetochores are correctly attached to the spindle apparatus.

116

Publications

5.9K

Citations

768

Authors

285

Institutions

Publications per year

2017–2026

34

Parents

Publications

116

Dependence of Paclitaxel Sensitivity on a Functional Spindle Assembly Checkpoint

Tamotsu Sudo, Masayuki Nitta, Hideyuki Saya et al. · Cancer Research · 2004 · 261 citations · Full text

, , +17

Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast.

Kevin Hardwick, Andrew W. Murray · The Journal of Cell Biology · 1995 · 231 citations · Full text

, , +17

Polo-like Kinase-1 Is Required for Bipolar Spindle Formation but Is Dispensable for Anaphase Promoting Complex/Cdc20 Activation and Initiation of Cytokinesis

Marcel A.T.M. van Vugt, Barbara C. M. van de Weerdt, Gerben Vader et al. · Journal of Biological Chemistry · 2004 · 203 citations · Full text

, , +17

Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells

Akihiro Ohashi, Momoko Ohori, Kenichi Iwai et al. · Nature Communications · 2015 · 200 citations · Full text

, , +17

Mutations in the Essential Spindle Checkpoint Gene <i>bub1</i> Cause Chromosome Missegregation and Fail to Block Apoptosis in <i>Drosophila</i>

Joydeep Basu, Hassan Bousbaa, Elsa Logarinho et al. · The Journal of Cell Biology · 1999 · 192 citations · Full text

, , +17

1–5 of 116

Authors

768

  1. AM
    Ann M. Rose

    University of British Columbia, Canada

    3 publications · 215 citations

    3

    h-index

  2. HB
    Hassan Bousbaa

    Universidade do Porto, Portugal

    3 publications · 313 citations

    3

    h-index

  3. BX
    Bo Xiong

    Nanjing Agricultural University, China

    3 publications · 113 citations

    3

    h-index

  4. RH
    René H. Medema

    The Netherlands Cancer Institute, Netherlands

    3 publications · 273 citations

    3

    h-index

  5. DH
    Dai Hirata

    Hiroshima University, Japan

    2 publications · 41 citations

    2

    h-index

1–5 of 768

Institutions

285

  1. University of Toronto

    Toronto, Canada

    5 h-index

    10 publications

    696 citations

  2. University of British Columbia

    Vancouver, Canada

    4 h-index

    9 publications

    540 citations

  3. National Institutes of Health

    Bethesda, United States

    4 h-index

    11 publications

    329 citations

  4. Hiroshima University

    Hiroshima, Japan

    4 h-index

    14 publications

    366 citations

  5. Inserm

    Paris, France

    4 h-index

    6 publications

    541 citations

  6. Oncode Institute

    Utrecht, Netherlands

    3 h-index

    10 publications

    584 citations

  7. University of Washington

    Seattle, United States

    3 h-index

    9 publications

    493 citations

  8. Mayo Clinic

    Rochester, United States

    3 h-index

    14 publications

    535 citations

1–8 of 285

Venues

  1. Cell Cycle

    8 publications · 242 citations

    8

    h-index

  2. Molecular Biology of the Cell

    MBC · 8 publications · 489 citations

    8

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 433 citations

    6

    h-index

  4. Genetics

    5 publications · 203 citations

    5

    h-index

  5. Journal of Cell Science

    4 publications · 248 citations

    4

    h-index

1–5