Concepedia

Sodium-taurocholate Cotransporting Polypeptide

Sodium-Taurocholate Cotransporting Polypeptide is a hepatic membrane transport protein that mediates the uptake of conjugated bile salts into hepatocytes by coupling their translocation to the electrochemical gradient of sodium ions, distinguishing it among solute carrier transporters through its substrate specificity for taurocholate and sodium-dependent mechanism.

334

Publications

23.6K

Citations

1.7K

Authors

492

Institutions

Publications per year

2017–2026

103

Variants

NtcpSlc10a1

Parents

Publications

334

Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

Huan Yan, Guocai Zhong, Guangwei Xu et al. · eLife · 2012 · 2.1K citations · Full text

, , +13

Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes

Yi Ni, Florian A. Lempp, Stefan Mehrle et al. · Gastroenterology · 2013 · 766 citations · Full text

, , +11

OATP and P-Glycoprotein Transporters Mediate the Cellular Uptake and Excretion of Fexofenadine

Mirjana Cvetković, Brenda F. Leake, Martin F. Fromm et al. · Drug Metabolism and Disposition · 1999 · 595 citations

, , +17

Expression cloning of a rat liver Na(+)-independent organic anion transporter.

Emmanuel Jacquemin, Bruno Hagenbuch, Bruno Stieger et al. · Proceedings of the National Academy of Sciences · 1994 · 537 citations

, , +12

Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.

Bruno Hagenbuch, P.J. Meier · Journal of Clinical Investigation · 1994 · 459 citations · Full text

, , +13

1–5 of 334

Authors

1.7K

  1. PJ
    Peter J. Meier

    University Hospital of Zurich, Switzerland

    21 publications · 2.3K citations

    20

    h-index

  2. BS
    Bruno Stieger

    University Hospital of Zurich, Switzerland

    20 publications · 2.2K citations

    19

    h-index

  3. BH
    Bruno Hagenbuch

    University Hospital of Zurich, Switzerland

    19 publications · 2.3K citations

    17

    h-index

  4. KW
    Koichi Watashi

    National Institute of Infectious Diseases, Japan

    17 publications · 1.4K citations

    16

    h-index

  5. TW
    Takaji Wakita

    National Institute of Infectious Diseases, Japan

    16 publications · 1.3K citations

    15

    h-index

1–5 of 1.7K

Institutions

492

  1. University Hospital of Zurich

    Zurich, Switzerland

    21 h-index

    67 publications

    9K citations

  2. National Institute of Infectious Diseases

    Tokyo, Japan

    17 h-index

    98 publications

    8.8K citations

  3. Justus-Liebig-Universität Gießen

    Giessen, Germany

    16 h-index

    116 publications

    4.5K citations

  4. German Center for Infection Research

    Braunschweig, Germany

    16 h-index

    49 publications

    3.9K citations

  5. National Institute of Biological Sciences, Beijing

    Beijing, China

    15 h-index

    122 publications

    49.6K citations

  6. University of Kansas Medical Center

    Kansas City, United States

    14 h-index

    48 publications

    4.4K citations

  7. The University of Tokyo

    Tokyo, Japan

    13 h-index

    26 publications

    2.9K citations

  8. Inserm

    Paris, France

    12 h-index

    52 publications

    3.7K citations

1–8 of 492

Venues

  1. Hepatology

    30 publications · 2.4K citations

    27

    h-index

  2. Drug Metabolism and Disposition

    23 publications · 2.8K citations

    20

    h-index

  3. 19

    h-index

  4. Journal of Biological Chemistry

    JBC · 14 publications · 1.2K citations

    14

    h-index

  5. Scientific Reports

    13 publications · 561 citations

    13

    h-index

1–5