Concepedia

Site-specific Modification Engineering

Site-Specific Modification Engineering is a methodological framework within post-translational modification engineering that enables the precise, targeted alteration of specific amino acid residues in a protein to achieve defined biochemical or functional outcomes.

109

Publications

7.5K

Citations

600

Authors

218

Institutions

Publications per year

2017–2026

37

Parents

Publications

109

A General Method for Site-specific Incorporation of Unnatural Amino Acids into Proteins

Christopher J. Noren, Spencer J. Anthony‐Cahill, Michael Griffith et al. · Science · 1989 · 1K citations

, , +14

A synthetic IgG-binding domain based on staphylococcal protein A

Björn Nilsson, Tomas Moks, Birger Jansson et al. · Protein Engineering Design and Selection · 1987 · 762 citations

, , +13

Introduction of amino groups into acid-resistant MOFs for enhanced U(<scp>vi</scp>) sorption

Zhi-Qiang Bai, Li‐Yong Yuan, Lin Zhu et al. · Journal of Materials Chemistry A · 2014 · 461 citations

, , +12

Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode Nɛ-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification

T. Yanagisawa, Ryohei Ishii, Ryuya Fukunaga et al. · Chemistry & Biology · 2008 · 343 citations

, , +17

Chemo- and Regioselective Lysine Modification on Native Proteins

María João Matos, Bruno L. Oliveira, Nuria Martínez‐Sáez et al. · Journal of the American Chemical Society · 2018 · 303 citations · Full text

, , +13

1–5 of 109

Authors

600

  1. BG
    Benjamin G. Davis

    University of Oxford, United Kingdom

    4 publications · 246 citations

    4

    h-index

  2. LW
    Lei Wang

    University of California, San Francisco, United States

    4 publications · 352 citations

    4

    h-index

  3. GJ
    Gonçalo J. L. Bernardes

    University of Cambridge, United Kingdom

    4 publications · 439 citations

    4

    h-index

  4. JL
    Jun Liu

    University of Delaware, United States

    3 publications · 157 citations

    3

    h-index

  5. PG
    Peter G. Schultz

    Scripps Research Institute, United States

    3 publications · 1.3K citations

    3

    h-index

1–5 of 600

Institutions

218

  1. University of California, San Francisco

    San Francisco, United States

    5 h-index

    16 publications

    1K citations

  2. Chinese Academy of Sciences

    Beijing, China

    5 h-index

    14 publications

    3.6K citations

  3. University of Oxford

    Oxford, United Kingdom

    4 h-index

    29 publications

    1.4K citations

  4. ETH Zurich

    Zurich, Switzerland

    4 h-index

    14 publications

    837 citations

  5. University of Delaware

    Newark, United States

    4 h-index

    13 publications

    510 citations

  6. National Institutes of Health

    Bethesda, United States

    4 h-index

    11 publications

    377 citations

  7. Tsinghua University

    Beijing, China

    3 h-index

    10 publications

    314 citations

  8. Systems Biology Institute

    Tokyo, Japan

    3 h-index

    15 publications

    2.6K citations

1–8 of 218

Venues

  1. Bioconjugate Chemistry

    13 publications · 681 citations

    13

    h-index

  2. Journal of the American Chemical Society

    JACS · 11 publications · 838 citations

    11

    h-index

  3. ChemBioChem

    7 publications · 244 citations

    7

    h-index

  4. Chemical Science

    6 publications · 261 citations

    6

    h-index

  5. Chemical Communications

    ChemComm · 5 publications · 285 citations

    5

    h-index

1–5