Concepedia

Sirolimus Interactions

Sirolimus Interactions is a pharmacological construct that denotes the modulatory effects of sirolimus on the pharmacokinetics and pharmacodynamics of co-administered agents in transplant recipients, distinguished by its mechanistic basis in mTOR inhibition and P-glycoprotein-mediated drug disposition.

69

Publications

3.1K

Citations

337

Authors

121

Institutions

Publications per year

2017–2026

3

Parents

Publications

69

Pharmacokinetic Interactions Augment Toxicities of Sirolimus/Cyclosporine Combinations

Hemangshu Podder, Stanislaw M. Stepkowski, Kimberly L. Napoli et al. · Journal of the American Society of Nephrology · 2001 · 221 citations

, , +17

Exposure-response relationships and drug interactions of sirolimus

James J. Zimmerman · The AAPS Journal · 2004 · 122 citations · Full text

, , +14

Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine–sirolimus interaction

Dany Anglicheau, Nicolas Pallet, Marion Rabant et al. · Kidney International · 2006 · 120 citations · Full text

, , +12

Voriconazole and Sirolimus Coadministration after Allogeneic Hematopoietic Stem Cell Transplantation

Francisco M. Marty, Colleen Lowry, Corey Cutler et al. · Biology of Blood and Marrow Transplantation · 2006 · 112 citations · Full text

, , +14

IMMUNOSUPPRESSIVE EFFECTS OF FTY720 ALONE OR IN COMBINATION WITH CYCLOSPORINE AND/OR SIROLIMUS1

Mouer Wang, Neelam Tejpal, Xumei Qu et al. · Transplantation · 1998 · 100 citations

, , +17

1–5 of 69

Authors

337

  1. SM
    Stanislaw M. Stepkowski

    The University of Texas at Austin, United States

    8 publications · 650 citations

    8

    h-index

  2. BD
    Barry D. Kahan

    The University of Texas at Austin, United States

    7 publications · 564 citations

    7

    h-index

  3. KL
    Kimberly L. Napoli

    The University of Texas at Austin, United States

    5 publications · 481 citations

    5

    h-index

  4. TC
    Ting‐Chao Chou

    Memorial Sloan Kettering Cancer Center, United States

    5 publications · 490 citations

    5

    h-index

  5. WJ
    William J. Jusko

    University at Buffalo, State University of New York, United States

    3 publications · 142 citations

    3

    h-index

1–5 of 337

Institutions

121

  1. The University of Texas at Austin

    Austin, United States

    7 h-index

    31 publications

    3K citations

  2. Texas Medical Center

    Houston, United States

    4 h-index

    7 publications

    387 citations

  3. Inserm

    Paris, France

    4 h-index

    19 publications

    1.4K citations

  4. University at Buffalo, State University of New York

    Buffalo, United States

    3 h-index

    4 publications

    174 citations

  5. National Institutes of Health

    Bethesda, United States

    2 h-index

    18 publications

    514 citations

  6. Université Paris Cité

    Paris, France

    2 h-index

    9 publications

    954 citations

  7. Universidade Federal de São Paulo

    São Paulo, Brazil

    2 h-index

    15 publications

    408 citations

  8. Wayne State University

    Detroit, United States

    2 h-index

    4 publications

    112 citations

1–8 of 121

Venues

  1. Transplantation

    9 publications · 441 citations

    9

    h-index

  2. Transplantation Proceedings

    6 publications · 209 citations

    6

    h-index

  3. Therapeutic Drug Monitoring

    4 publications · 148 citations

    4

    h-index

  4. Clinical Pharmacology & Therapeutics

    CPT · 3 publications · 121 citations

    3

    h-index

  5. PubMed

    Repository · 3 publications · 124 citations

    3

    h-index

1–5