Concepedia

Single-turnover Kinetics

Single-Turnover Kinetics is a kinetic measurement technique in enzyme kinetics that belongs to the class of fast reaction methods, distinguished by its focus on monitoring the conversion of a single substrate molecule to product per enzyme molecule under conditions where substrate is in limiting excess relative to enzyme.

325

Publications

19.6K

Citations

1.1K

Authors

313

Institutions

Publications per year

2017–2026

23

Parents

Publications

325

Millisecond Kinetics on a Microfluidic Chip Using Nanoliters of Reagents

Helen Song, Rustem F. Ismagilov · Journal of the American Chemical Society · 2003 · 683 citations · Full text

, , +17

Mechanism of GroEL action: Productive release of polypeptide from a sequestered position under groes

Jonathan S. Weissman, Corinne M. Hohl, Oleg Kovalenko et al. · Cell · 1995 · 422 citations · Full text

, , +17

Toxicity of Antiviral Nucleoside Analogs and the Human Mitochondrial DNA Polymerase

Allison A. Johnson, Adrian S. Ray, Jeremiah W. Hanes et al. · Journal of Biological Chemistry · 2001 · 401 citations · Full text

, , +17

An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics

Isaac Wong, Smita S. Patel, Kenneth A. Johnson · Biochemistry · 1991 · 370 citations

, , +9

Large Kinetic Isotope Effects in Methane Oxidation Catalyzed by Methane Monooxygenase:  Evidence for C−H Bond Cleavage in a Reaction Cycle Intermediate

Jeremy C. Nesheim, John D. Lipscomb · Biochemistry · 1996 · 271 citations

, , +16

1–5 of 325

Authors

1.1K

  1. JD
    John D. Lipscomb

    University of Minnesota, United States

    13 publications · 1.4K citations

    13

    h-index

  2. KA
    Kenneth A. Johnson

    The University of Texas at Austin, United States

    8 publications · 933 citations

    8

    h-index

  3. DJ
    Dennis J. Stuehr

    Cleveland Clinic Lerner College of Medicine, United States

    5 publications · 269 citations

    5

    h-index

  4. KS
    Karen S. Anderson

    Yale University, United States

    5 publications · 704 citations

    5

    h-index

  5. EM
    Eckard Münck

    Carnegie Mellon University, United States

    4 publications · 285 citations

    4

    h-index

1–5 of 1.1K

Institutions

313

  1. University of Minnesota

    Minneapolis, United States

    11 h-index

    36 publications

    2.9K citations

  2. Stanford University

    Stanford, United States

    10 h-index

    30 publications

    2K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    26 publications

    839 citations

  4. Yale University

    New Haven, United States

    9 h-index

    32 publications

    5.1K citations

  5. Pennsylvania State University

    State College, United States

    8 h-index

    23 publications

    2.5K citations

  6. University of Michigan

    Ann Arbor, United States

    8 h-index

    25 publications

    1K citations

  7. University of Utah

    Salt Lake City, United States

    8 h-index

    23 publications

    2K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    7 h-index

    23 publications

    1.7K citations

1–8 of 313

Venues

  1. Biochemistry

    104 publications · 5.5K citations

    45

    h-index

  2. Journal of Biological Chemistry

    JBC · 67 publications · 4.9K citations

    44

    h-index

  3. Journal of the American Chemical Society

    JACS · 29 publications · 2.6K citations

    24

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 1.1K citations

    12

    h-index

  5. Nucleic Acids Research

    11 publications · 480 citations

    11

    h-index

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