Concepedia

Single-turnover Catalysis

Single-Turnover Catalysis is a catalytic mechanism in which a catalyst participates in exactly one complete reaction cycle, converting a single substrate molecule into product before dissociating or becoming inactivated, thereby enabling precise kinetic and mechanistic analysis of individual catalytic events.

73

Publications

4.4K

Citations

286

Authors

104

Institutions

Publications per year

2017–2026

10

Parents

Publications

73

Mechanistic Studies of the Reaction of Reduced Methane Monooxygenase Hydroxylase with Dioxygen and Substrates

Ann M. Valentine, Shannon S. Stahl, Stephen J. Lippard · Journal of the American Chemical Society · 1999 · 248 citations

, , +14

Ribozyme-catalyzed and nonenzymic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom

Daniel Herschlag, Joseph A. Piccirilli, Thomas R. Cech · Biochemistry · 1991 · 230 citations

, , +15

Single Turnover Chemistry and Regulation of O2Activation by the Oxygenase Component of Naphthalene 1,2-Dioxygenase

Matt D. Wolfe, J.V. Parales, David T. Gibson et al. · Journal of Biological Chemistry · 2001 · 179 citations · Full text

, , +17

Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9

Austin T. Raper, Anthony A. Stephenson, Zucai Suo · Journal of the American Chemical Society · 2018 · 169 citations

, , +13

Rapid Kinetic Studies Link Tetrahydrobiopterin Radical Formation to Heme-dioxy Reduction and Arginine Hydroxylation in Inducible Nitric-oxide Synthase

Chin‐Chuan Wei, Zhiqiang Wang, Qian Wang et al. · Journal of Biological Chemistry · 2001 · 128 citations · Full text

, , +17

1–5 of 73

Authors

286

  1. JD
    John D. Lipscomb

    University of Minnesota, United States

    5 publications · 513 citations

    5

    h-index

  2. DJ
    Dennis J. Stuehr

    Cleveland Clinic Lerner College of Medicine, United States

    5 publications · 227 citations

    5

    h-index

  3. DD
    Debra Dunaway‐Mariano

    University of New Mexico, United States

    3 publications · 123 citations

    3

    h-index

  4. CW
    Chin‐Chuan Wei

    Cleveland Clinic, United States

    3 publications · 197 citations

    3

    h-index

  5. WX
    Weilin Xu

    Changchun Institute of Applied Chemistry, China

    3 publications · 218 citations

    3

    h-index

1–5 of 286

Institutions

104

  1. Cornell University

    Ithaca, United States

    6 h-index

    28 publications

    1.8K citations

  2. University of Minnesota

    Minneapolis, United States

    4 h-index

    18 publications

    1.5K citations

  3. Cleveland Clinic Lerner College of Medicine

    Cleveland, United States

    4 h-index

    10 publications

    278 citations

  4. Stanford University

    Stanford, United States

    4 h-index

    11 publications

    576 citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    4 h-index

    15 publications

    1.3K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    11 publications

    772 citations

  7. Cleveland Clinic

    Cleveland, United States

    3 h-index

    20 publications

    1.4K citations

  8. Oregon Health & Science University

    Portland, United States

    3 h-index

    9 publications

    491 citations

1–8 of 104

Venues

  1. Biochemistry

    16 publications · 758 citations

    15

    h-index

  2. Journal of the American Chemical Society

    JACS · 14 publications · 1.1K citations

    14

    h-index

  3. Journal of Biological Chemistry

    JBC · 13 publications · 967 citations

    12

    h-index

  4. RNA

    3 publications · 103 citations

    3

    h-index

  5. FEBS Journal

    2 publications · 30 citations

    2

    h-index

1–5