Concepedia

Single-molecule Image Analysis

Single-Molecule Image Analysis is a computational methodology that distinguishes itself by enabling the detection, localization, tracking, and quantification of individual molecules in microscopy images through statistical modeling and image processing techniques tailored to the unique challenges of low signal-to-noise ratios and sparse molecular signals.

291

Publications

22.2K

Citations

1.3K

Authors

425

Institutions

Publications per year

2017–2026

116

Parents

Publications

291

ThunderSTORM: a comprehensive ImageJ plug-in for PALM and STORM data analysis and super-resolution imaging

Martin Ovesný, Pavel Křížek, Josef Borkovec et al. · Bioinformatics · 2014 · 1.7K citations · Full text

, , +16

Single-Molecule Speckle Analysis of Actin Filament Turnover in Lamellipodia

Naoki Watanabe, Timothy J. Mitchison · Science · 2002 · 499 citations

, , +16

smiFISH and FISH-quant – a flexible single RNA detection approach with super-resolution capability

Nikolay Tsanov, Aubin Samacoïts, Racha Chouaib et al. · Nucleic Acids Research · 2016 · 488 citations · Full text

, , +17

New directions in single-molecule imaging and analysis

W. E. Moerner · Proceedings of the National Academy of Sciences · 2007 · 443 citations · Full text

, , +15

Quantitative evaluation of software packages for single-molecule localization microscopy

Daniel Sage, Hagai Kirshner, Thomas Pengo et al. · Nature Methods · 2015 · 408 citations · Full text

, , +16

1–5 of 291

Authors

1.3K

  1. MH
    Mike Heilemann

    Goethe University Frankfurt, Germany

    11 publications · 1K citations

    11

    h-index

  2. WE
    W. E. Moerner

    Stanford University, United States

    8 publications · 1.1K citations

    8

    h-index

  3. RJ
    Raimund J. Ober

    The University of Texas Southwestern Medical Center, United States

    7 publications · 1K citations

    7

    h-index

  4. JR
    Jonas Ries

    European Molecular Biology Laboratory, Germany

    7 publications · 644 citations

    7

    h-index

  5. SM
    Sebastian Malkusch

    Goethe University Frankfurt, Germany

    6 publications · 716 citations

    6

    h-index

1–5 of 1.3K

Institutions

425

  1. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    53 publications

    8.3K citations

  2. Heidelberg University

    Heidelberg, Germany

    10 h-index

    33 publications

    1.1K citations

  3. École Polytechnique Fédérale de Lausanne

    Lausanne, Switzerland

    10 h-index

    34 publications

    6.2K citations

  4. Goethe University Frankfurt

    Frankfurt am Main, Germany

    9 h-index

    28 publications

    2.2K citations

  5. University of Würzburg

    Würzburg, Germany

    9 h-index

    26 publications

    1.3K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    8 h-index

    14 publications

    1.4K citations

  7. Chinese Academy of Sciences

    Beijing, China

    8 h-index

    41 publications

    1.6K citations

  8. Washington University in St. Louis

    St Louis, United States

    7 h-index

    26 publications

    924 citations

1–8 of 425

Venues

  1. Biophysical Journal

    16 publications · 1.3K citations

    15

    h-index

  2. Nature Methods

    13 publications · 2.2K citations

    13

    h-index

  3. Nature Communications

    11 publications · 845 citations

    11

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 1.7K citations

    10

    h-index

  5. Scientific Reports

    9 publications · 417 citations

    9

    h-index

1–5