Concepedia

Single-compartment Kinetics

Single-Compartment Kinetics is a pharmacokinetic modeling approach that belongs to the class of compartmental models, distinguished by its assumption that the body behaves as a single, kinetically homogeneous unit with instantaneous and uniform distribution of the administered substance throughout the system.

55

Publications

2.8K

Citations

212

Authors

93

Institutions

Publications per year

2017–2026

5

Variants

Single-compartment Model

Parents

Publications

55

Shortcomings in Pharmacokinetic Analysis by Conceiving the Body to Exhibit Properties of a Single Compartment

Sidney Riegelman, J.C.K. Loo, Malcolm Rowland · Journal of Pharmaceutical Sciences · 1968 · 381 citations

, , +16

Experimental validation of measurements of glucose turnover in nonsteady state.

J. Radziuk, Kenneth H. Norwich, M. Vranić · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 277 citations

, , +15

Estimation of Glomerular Filtration Rate from Plasma Clearance of 51-Chromium Edetic Acid

C Chantler, T M Barratt · Archives of Disease in Childhood · 1972 · 256 citations · Full text

, , +17

Determination of Iodothyronine Absorption and Conversion of L-Thyroxine (T4) to L-Triiodothyronine (T3) using Turnover Rate Techniques

Martin I. Surks, Alan R. Schadlow, Jerrold M. Stock et al. · Journal of Clinical Investigation · 1973 · 223 citations · Full text

, , +14

Some Formal Approaches to the Analysis of Kinetic Data in Terms of Linear Compartmental Systems

Mones Berman, Ezra Shahn, Marjory F. Weiss · Biophysical Journal · 1962 · 165 citations

, , +16

1–5 of 55

Authors

212

  1. CC
    Claudio Cobelli

    University of Padua, Italy

    4 publications · 230 citations

    4

    h-index

  2. AD
    A. Domínguez‐Gil

    Universidad de Salamanca, Spain

    2 publications · 54 citations

    2

    h-index

  3. AS
    Arkadiusz Sitek

    Harvard University, United States

    2 publications · 44 citations

    2

    h-index

  4. AC
    Andrea Caumo

    San Raffaele University of Rome, Italy

    2 publications · 129 citations

    2

    h-index

  5. RG
    Robert G. Sheiman

    Beth Israel Deaconess Medical Center, United States

    2 publications · 44 citations

    2

    h-index

1–5 of 212

Institutions

93

  1. University of Padua

    Padua, Italy

    4 h-index

    13 publications

    716 citations

  2. University of Southern California

    Los Angeles, United States

    2 h-index

    6 publications

    204 citations

  3. Harvard University

    Cambridge, United States

    2 h-index

    2 publications

    44 citations

  4. University of Washington

    Seattle, United States

    2 h-index

    2 publications

    129 citations

  5. Louisiana State University

    Baton Rouge, United States

    2 h-index

    2 publications

    115 citations

  6. Beth Israel Deaconess Medical Center

    Boston, United States

    2 h-index

    2 publications

    44 citations

  7. San Raffaele University of Rome

    Rome, Italy

    2 h-index

    2 publications

    129 citations

  8. University of Minnesota

    Minneapolis, United States

    2 h-index

    8 publications

    316 citations

1–8 of 93

Venues

  1. 5

    h-index

  2. PubMed

    Repository · 4 publications · 64 citations

    4

    h-index

  3. Computer Methods and Programs in Biomedicine

    2 publications · 53 citations

    2

    h-index

  4. British Journal Of Nutrition

    BJN · 2 publications · 40 citations

    2

    h-index

  5. IEEE Transactions on Biomedical Engineering

    2 publications · 65 citations

    2

    h-index

1–5