Concepedia

Sequence-structure Side-chain Compatibility

Sequence–Structure Side-Chain Compatibility is a computational metric that evaluates the thermodynamic favorability and geometric feasibility of amino acid side-chain conformations given a fixed protein backbone structure, distinguishing it from general folding models by specifically quantifying the compatibility between a protein sequence and its predicted or observed three-dimensional structure based on side-chain packing interactions.

4

Publications

232

Citations

14

Authors

5

Institutions

Publications per year

2017–2026

0

Parents

Publications

4

DNA-Templated Polymerization of Side-Chain-Functionalized Peptide Nucleic Acid Aldehydes

Ralph E. Kleiner, Yevgeny Brudno, Michael E. Birnbaum et al. · Journal of the American Chemical Society · 2008 · 149 citations · Full text

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Denatured proteins and early folding intermediates simulated in a reduced conformational space.

Sebastian Kmiecik, Mateusz Kurciński, Aleksandra Rutkowska et al. · Acta Biochimica Polonica · 2005 · 29 citations · Full text

, , +17

Effects of Alternative Side Chain Pairings and Reverse Turn Sequences on Antiparallel Sheet Structure in β-Peptide Hairpins

Joseph M. Langenhan, Samuel H. Gellman · Organic Letters · 2004 · 28 citations

, , +17

Threading Using Neural nEtwork (TUNE): the measure ofprotein sequence—structure compatibility

Kuang Lin, Alex C.W. May, William R. Taylor · Bioinformatics · 2002 · 26 citations

, , +16

1–4 of 4

Authors

14

  1. DG
    Dominik Gront

    University of Warsaw, Poland

    1 publications · 29 citations

    1

    h-index

  2. MK
    Mateusz Kurciński

    University of Warsaw, Poland

    1 publications · 29 citations

    1

    h-index

  3. WR
    William R. Taylor

    National Institute for Medical Research, Tanzania

    1 publications · 26 citations

    1

    h-index

  4. AC
    Alex C.W. May

    Birkbeck, University of London, United Kingdom

    1 publications · 26 citations

    1

    h-index

  5. JM
    Joseph M. Langenhan

    Seattle University, United States

    1 publications · 28 citations

    1

    h-index

1–5 of 14

Institutions

5

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    4 publications

    596 citations

  2. University of Wisconsin–Madison

    Madison, United States

    1 h-index

    2 publications

    56 citations

  3. University of Warsaw

    Warsaw, Poland

    1 h-index

    5 publications

    145 citations

  4. Harvard University

    Cambridge, United States

    1 h-index

    4 publications

    596 citations

  5. London Institute for Mathematical Sciences

    London, United Kingdom

    1 h-index

    1 publications

    26 citations

1–5 of 5

Venues

  1. Journal of the American Chemical Society

    JACS · 1 publications · 149 citations

    1

    h-index

  2. Organic Letters

    OL · 1 publications · 28 citations

    1

    h-index

  3. Bioinformatics

    1 publications · 26 citations

    1

    h-index

  4. Acta Biochimica Polonica

    1 publications · 29 citations

    1

    h-index

1–4