Concepedia

Sequence Specificity Modeling

Sequence Specificity Modeling is a computational method that predicts the binding or cleavage preferences of molecular agents at target sites by characterizing the nucleotide or amino acid sequence features that distinguish high-affinity or functional sites from non-functional ones.

101

Publications

7.6K

Citations

422

Authors

195

Institutions

Publications per year

2017–2026

22

Parents

Publications

101

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

Marc Röttig, Marnix H. Medema, Kai Blin et al. · Nucleic Acids Research · 2011 · 631 citations · Full text

, , +14

Convolutional neural network architectures for predicting DNA–protein binding

Haoyang Zeng, Matthew D. Edwards, Ge Liu et al. · Bioinformatics · 2016 · 549 citations · Full text

, , +15

Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method

Bjoern Peters, Alessandro Sette · BMC Bioinformatics · 2005 · 529 citations · Full text

, , +13

Substrate and sequence specificity of a eukaryotic DNA methylase

Yosef Gruenbaum, Howard Cedar, Aharon Razin · Nature · 1982 · 439 citations

, , +9

Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)

Christian Rausch · Nucleic Acids Research · 2005 · 417 citations · Full text

, , +17

1–5 of 101

Authors

422

  1. HK
    Hidetoshi Kono

    National Institutes for Quantum Science and Technology, Japan

    3 publications · 119 citations

    3

    h-index

  2. RG
    Raluca Gordân

    Duke University, United States

    3 publications · 111 citations

    3

    h-index

  3. QM
    Quaid Morris

    University of Toronto, Canada

    3 publications · 509 citations

    3

    h-index

  4. TR
    Timothy R. Hughes

    University of Toronto, Canada

    3 publications · 509 citations

    3

    h-index

  5. AS
    Akinori Sarai

    Kyushu Institute of Technology, Japan

    3 publications · 119 citations

    3

    h-index

1–5 of 422

Institutions

195

  1. University of Washington

    Seattle, United States

    5 h-index

    34 publications

    1.1K citations

  2. Harvard University

    Cambridge, United States

    5 h-index

    15 publications

    1.5K citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    4 h-index

    14 publications

    2.7K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    15 publications

    897 citations

  5. Inserm

    Paris, France

    4 h-index

    16 publications

    625 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    8 publications

    264 citations

  7. Brigham and Women's Hospital

    Boston, United States

    3 h-index

    6 publications

    955 citations

  8. Columbia University

    New York, United States

    3 h-index

    8 publications

    286 citations

1–8 of 195

Venues

  1. Nucleic Acids Research

    15 publications · 1.6K citations

    13

    h-index

  2. Bioinformatics

    8 publications · 956 citations

    8

    h-index

  3. BMC Bioinformatics

    6 publications · 955 citations

    6

    h-index

  4. Journal of the American Chemical Society

    JACS · 5 publications · 205 citations

    5

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 275 citations

    5

    h-index

1–5