Concepedia

Sensitization Thresholds

Sensitization Threshold is a theoretical construct in immunotoxicology that denotes the minimum level of allergen exposure required to induce a persistent immunological sensitization associated with delayed-type hypersensitivity, distinguishing it from elicitation thresholds by focusing on the initiation rather than the manifestation of immune reactivity.

67

Publications

4.5K

Citations

246

Authors

96

Institutions

Publications per year

2017–2026

7

Parents

Publications

67

SENS-IS, a 3D reconstituted epidermis based model for quantifying chemical sensitization potency: Reproducibility and predictivity results from an inter-laboratory study

Françoise Cottrez, Elodie Boitel, Jean-Claude Ourlin et al. · Toxicology in Vitro · 2016 · 476 citations

, , +12

The Dermal Sensitisation Threshold—A TTC approach for allergic contact dermatitis

R.J. Safford · Regulatory Toxicology and Pharmacology · 2008 · 469 citations

, , +14

Extension of the Dermal Sensitisation Threshold (DST) approach to incorporate chemicals classified as reactive

R.J. Safford, A.M. Api, David W. Roberts et al. · Regulatory Toxicology and Pharmacology · 2015 · 440 citations

, , +11

Refinement of the Dermal Sensitisation Threshold (DST) approach using a larger dataset and incorporating mechanistic chemistry domains

R.J. Safford, Aynur O. Aptula, N. Gilmour · Regulatory Toxicology and Pharmacology · 2011 · 433 citations

, , +14

Phenotypic features of central sensitization

David A. Williams · Journal of Applied Biobehavioral Research · 2018 · 174 citations · Full text

, , +15

1–5 of 67

Authors

246

  1. RS
    R.J. Safford

    Unilever (United Kingdom), United Kingdom

    5 publications · 1.4K citations

    5

    h-index

  2. AA
    A.M. Api

    Research Institute for Fragrance Materials, United States

    4 publications · 534 citations

    4

    h-index

  3. RJ
    Rebecca J. Dearman

    AstraZeneca (United Kingdom), United Kingdom

    4 publications · 277 citations

    4

    h-index

  4. DA
    David A. Basketter

    Unilever (United Kingdom), United Kingdom

    3 publications · 298 citations

    3

    h-index

  5. DW
    David W. Roberts

    Liverpool John Moores University, United Kingdom

    3 publications · 480 citations

    3

    h-index

1–5 of 246

Institutions

96

  1. Unilever (United Kingdom)

    London, United Kingdom

    4 h-index

    12 publications

    2.7K citations

  2. Research Institute for Fragrance Materials

    Woodcliff Lake, United States

    4 h-index

    9 publications

    1.1K citations

  3. Liverpool John Moores University

    Liverpool, United Kingdom

    3 h-index

    3 publications

    480 citations

  4. Annamalai University

    Chidambaram, India

    3 h-index

    5 publications

    100 citations

  5. Jewish Hospital

    Cincinnati, United States

    3 h-index

    7 publications

    133 citations

  6. Johns Hopkins University

    Baltimore, United States

    3 h-index

    12 publications

    1.1K citations

  7. Temple University Hospital

    Philadelphia, United States

    2 h-index

    5 publications

    101 citations

  8. Kao Corporation (Japan)

    Tokyo, Japan

    2 h-index

    9 publications

    153 citations

1–8 of 96

Venues

  1. Regulatory Toxicology and Pharmacology

    RTP · 6 publications · 1.5K citations

    6

    h-index

  2. Journal of Allergy

    6 publications · 138 citations

    6

    h-index

  3. Toxicology in Vitro

    5 publications · 715 citations

    5

    h-index

  4. Contact Dermatitis

    3 publications · 172 citations

    3

    h-index

  5. Toxicology

    3 publications · 132 citations

    3

    h-index

1–5