Concepedia

Self-splicing Introns

Self-Splicing Intron is an intron that belongs to the class of catalytic RNA molecules and is distinguished by its ability to excise itself from a precursor RNA transcript without the requirement of a spliceosome or external protein enzymes, relying instead on intrinsic ribozyme activity.

369

Publications

30.3K

Citations

828

Authors

296

Institutions

Publications per year

2017–2026

22

Variants

Self-splicing Intron

Parents

Publications

369

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

Kelly Kruger, Paula J. Grabowski, Arthur J. Zaug et al. · Cell · 1982 · 2.3K citations

, , +14

Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing

J.H.D. Cate, Anne R. Gooding, Elaine R. Podell et al. · Science · 1996 · 1.2K citations

, , +17

SPLICING OF MESSENGER RNA PRECURSORS

Richard A. Padgett, Paula J. Grabowski, Maria M. Konarska et al. · Annual Review of Biochemistry · 1986 · 1.2K citations

, , +15

A general two-metal-ion mechanism for catalytic RNA.

Thomas A. Steitz, J A Steitz · Proceedings of the National Academy of Sciences · 1993 · 1.2K citations

, , +17

Splicing of Messenger RNA Precursors

Phillip A. Sharp · Science · 1987 · 922 citations

, , +15

1–5 of 369

Authors

828

  1. TR
    Thomas R. Cech

    Howard Hughes Medical Institute, United States

    27 publications · 5.5K citations

    23

    h-index

  2. PS
    Philip S. Perlman

    The University of Texas Southwestern Medical Center, United States

    19 publications · 2.1K citations

    19

    h-index

  3. AM
    Anna Marie Pyle

    Howard Hughes Medical Institute, United States

    19 publications · 2.1K citations

    17

    h-index

  4. DA
    David A. Shub

    University at Albany, State University of New York, United States

    13 publications · 1.1K citations

    13

    h-index

  5. FM
    François Michel

    Centre de Génétique Moléculaire, France

    14 publications · 919 citations

    13

    h-index

1–5 of 828

Institutions

296

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    29 h-index

    78 publications

    11.3K citations

  2. University of Colorado Boulder

    Boulder, United States

    23 h-index

    64 publications

    23.7K citations

  3. Yale University

    New Haven, United States

    22 h-index

    85 publications

    15.4K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    65 publications

    5.1K citations

  5. Centre de Génétique Moléculaire

    Gif-sur-Yvette, France

    16 h-index

    38 publications

    3K citations

  6. University at Albany, State University of New York

    Albany, United States

    13 h-index

    34 publications

    3K citations

  7. University of Rochester

    Rochester, United States

    11 h-index

    38 publications

    1.1K citations

  8. The University of Texas Southwestern Medical Center

    Dallas, United States

    11 h-index

    36 publications

    2.8K citations

1–8 of 296

Venues

  1. Nucleic Acids Research

    60 publications · 2.7K citations

    32

    h-index

  2. RNA

    33 publications · 1.3K citations

    22

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 23 publications · 2.9K citations

    21

    h-index

  4. Cell

    19 publications · 5.5K citations

    19

    h-index

  5. Biochemistry

    27 publications · 991 citations

    19

    h-index

1–5