Concepedia

Self-nonself Discrimination

Self-Nonself Discrimination is a theoretical framework in immunology that delineates the immune system's ability to distinguish endogenous molecules (self) from foreign entities (nonself) in order to initiate appropriate immune responses while maintaining tolerance to self-antigens.

148

Publications

20.7K

Citations

461

Authors

226

Institutions

Publications per year

2017–2026

18

Variants

Self-nonself Recognition

Parents

Publications

148

The Danger Model: A Renewed Sense of Self

Polly Matzinger · Science · 2002 · 4.2K citations

, , +13

Decoding the Patterns of Self and Nonself by the Innate Immune System

Ruslan Medzhitov, Charles A. Janeway · Science · 2002 · 2.2K citations

, , +17

A Theory of Self-Nonself Discrimination

Peter A. Bretscher, Melvin Cohn · Science · 1970 · 1.7K citations

, , +11

Self-nonself discrimination in a computer

Stephanie Forrest, Alan S. Perelson, Luke R. Allen et al. · 2002 · 1.3K citations

, , +14

Self-Nonself Discrimination in a Computer

Stephanie Forrest, Alan S. Perelson, Lawrence H. Allen et al. · 1994 · 993 citations

, , +14

1–5 of 148

Authors

461

  1. MC
    Melvin Cohn

    Salk Institute for Biological Studies, United States

    10 publications · 2.1K citations

    10

    h-index

  2. RE
    Rodney E. Langman

    Salk Institute for Biological Studies, United States

    5 publications · 159 citations

    5

    h-index

  3. AS
    Alan S. Perelson

    Los Alamos National Laboratory, United States

    4 publications · 3.1K citations

    4

    h-index

  4. TP
    Thomas Pradeu

    Centre National de la Recherche Scientifique, France

    3 publications · 590 citations

    3

    h-index

  5. DR
    Donald R. Forsdyke

    Queen's University, Canada

    3 publications · 72 citations

    3

    h-index

1–5 of 461

Institutions

226

  1. Salk Institute for Biological Studies

    La Jolla, United States

    11 h-index

    17 publications

    4K citations

  2. Harvard University

    Cambridge, United States

    5 h-index

    18 publications

    1.5K citations

  3. University College London

    London, United Kingdom

    4 h-index

    7 publications

    230 citations

  4. Sorbonne Université

    Paris, France

    4 h-index

    6 publications

    668 citations

  5. Hokkaido University

    Sapporo, Japan

    3 h-index

    14 publications

    640 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    7 publications

    5.2K citations

  7. Queen's University

    Kingston, Canada

    3 h-index

    3 publications

    72 citations

  8. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    16 publications

    824 citations

1–8 of 226

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 13 publications · 1.6K citations

    12

    h-index

  2. Science

    9 publications · 9.4K citations

    9

    h-index

  3. The Journal of Immunology

    JI · 7 publications · 259 citations

    7

    h-index

  4. Journal of Theoretical Biology

    5 publications · 761 citations

    5

    h-index

  5. Nature

    4 publications · 889 citations

    4

    h-index

1–5