Concepedia

Self-immolative Fluorogenic Probes

Self-Immolative Fluorogenic Probes is a type of fluorogenic bioorthogonal probe that, upon a specific bioorthogonal reaction, undergoes a spontaneous intramolecular rearrangement to release a fluorescent reporter, distinguishing it from other fluorogenic probes by its traceless, multi-step activation mechanism enabling signal amplification and reduced background fluorescence.

17

Publications

764

Citations

81

Authors

44

Institutions

Publications per year

2017–2026

8

Parents

Publications

17

Thiol–Chromene “Click” Reaction Triggered Self-Immolative for NIR Visualization of Thiol Flux in Physiology and Pathology of Living Cells and Mice

Yu-Tao Yang, Tingting Zhou, Ming Jin et al. · Journal of the American Chemical Society · 2019 · 179 citations

, , +17

Self-immolative dendritic probe for direct detection of triacetone triperoxide

Eran Sella, Doron Shabat · Chemical Communications · 2008 · 94 citations

, , +15

Probing biotin receptors in cancer cells with rationally designed fluorogenic squaraine dimers

Kyong Tkhe Fam, Mayeul Collot, Andrey S. Klymchenko · Chemical Science · 2020 · 79 citations · Full text

, , +17

Development of a New Nonpeptidic Self-Immolative Spacer. Application to the Design of Protease Sensing Fluorogenic Probes

Yves Meyer, Jean‐Alexandre Richard, Marc Massonneau et al. · Organic Letters · 2008 · 59 citations

, , +17

A comparative study of the self-immolation of para-aminobenzylalcohol and hemithioaminal-based linkers in the context of protease-sensitive fluorogenic probes

Yves Meyer, Jean‐Alexandre Richard, Bruno Delest et al. · Organic & Biomolecular Chemistry · 2010 · 59 citations

, , +17

1–5 of 17

Authors

81

  1. AG
    Arnaud Gautier

    Centre National de la Recherche Scientifique, France

    2 publications · 55 citations

    2

    h-index

  2. RO
    Ryszard Ostaszewski

    Institute of Organic Chemistry, Poland

    2 publications · 42 citations

    2

    h-index

  3. PP
    Philippe Pelupessy

    Centre National de la Recherche Scientifique, France

    2 publications · 55 citations

    2

    h-index

  4. TL
    Thomas Le Saux

    Centre National de la Recherche Scientifique, France

    2 publications · 55 citations

    2

    h-index

  5. JR
    Jean‐Alexandre Richard

    Agency for Science, Technology and Research, Singapore

    2 publications · 118 citations

    2

    h-index

1–5 of 81

Institutions

44

  1. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    20 publications

    676 citations

  2. École Normale Supérieure - PSL

    Paris, France

    2 h-index

    14 publications

    385 citations

  3. Sorbonne Université

    Paris, France

    2 h-index

    16 publications

    440 citations

  4. Université de Rouen Normandie

    Rouen, France

    2 h-index

    7 publications

    413 citations

  5. Laboratoire des Biomolécules

    Paris, France

    2 h-index

    2 publications

    55 citations

  6. Polish Academy of Sciences

    Warsaw, Poland

    2 h-index

    7 publications

    129 citations

  7. Processus d'Activation Sélective par Transfert d'Énergie Uni-électronique ou Radiatif

    Paris, France

    2 h-index

    14 publications

    385 citations

  8. Institute of Organic Chemistry

    Warsaw, Poland

    2 h-index

    7 publications

    129 citations

1–8 of 44

Venues

  1. Chemical Communications

    ChemComm · 3 publications · 146 citations

    3

    h-index

  2. The Analyst

    2 publications · 73 citations

    2

    h-index

  3. Sensors and Actuators B Chemical

    2 publications · 44 citations

    2

    h-index

  4. Organic & Biomolecular Chemistry

    2 publications · 74 citations

    2

    h-index

  5. Angewandte Chemie

    1 publications · 15 citations

    1

    h-index

1–5