Concepedia

Segmentation Clock Modeling

Segmentation Clock Modeling is a computational framework that formalizes the spatiotemporal dynamics of oscillatory gene expression underlying vertebrate somitogenesis, distinguishing itself by quantitatively representing the periodic activation of signaling pathways that govern segmental patterning in embryonic development.

60

Publications

6.2K

Citations

287

Authors

123

Institutions

Publications per year

2017–2026

20

Parents

Publications

60

Notch signalling and the synchronization of the somite segmentation clock

Yun‐Jin Jiang, Birgit L. Aerne, Lucy Smithers et al. · Nature · 2000 · 559 citations

, , +14

Periodic Notch inhibition by Lunatic Fringe underlies the chick segmentation clock

J. Kim Dale, Marta Maroto, Mary‐Lee Dequéant et al. · Nature · 2003 · 324 citations

, , +12

Noise-resistant and synchronized oscillation of the segmentation clock

Kazuki Horikawa, Kana Ishimatsu, Eiichi Yoshimoto et al. · Nature · 2006 · 273 citations

, , +12

Species-specific segmentation clock periods are due to differential biochemical reaction speeds

Mitsuhiro Matsuda, Hanako Hayashi, Jordi García‐Ojalvo et al. · Science · 2020 · 259 citations · Full text

, , +14

Instability of Hes7 protein is crucial for the somite segmentation clock

Hiromi Hirata, Yasumasa Bessho, Hiroshi Kokubu et al. · Nature Genetics · 2004 · 254 citations

, , +8

1–5 of 60

Authors

287

  1. RK
    Ryoichiro Kageyama

    Kyoto University, Japan

    7 publications · 1.5K citations

    7

    h-index

  2. AC
    Andrew C. Oates

    Max Planck Institute of Molecular Cell Biology and Genetics, Germany

    6 publications · 479 citations

    6

    h-index

  3. EM
    Ertuğrul M. Özbudak

    Albert Einstein College of Medicine, United States

    6 publications · 529 citations

    6

    h-index

  4. OP
    Olivier Pourquié

    Centre National de la Recherche Scientifique, France

    5 publications · 1.1K citations

    5

    h-index

  5. JK
    J. Kim Dale

    University of Dundee, United Kingdom

    5 publications · 621 citations

    5

    h-index

1–5 of 287

Institutions

123

  1. Kyoto University

    Kyoto, Japan

    9 h-index

    51 publications

    10.5K citations

  2. Max Planck Institute of Molecular Cell Biology and Genetics

    Dresden, Germany

    6 h-index

    15 publications

    1.6K citations

  3. Harvard University

    Cambridge, United States

    5 h-index

    22 publications

    3.1K citations

  4. Japan Science and Technology Agency

    Tokyo, Japan

    5 h-index

    10 publications

    1.6K citations

  5. Albert Einstein College of Medicine

    Bronx, United States

    4 h-index

    11 publications

    450 citations

  6. Max Planck Institute for the Physics of Complex Systems

    Dresden, Germany

    4 h-index

    11 publications

    1.2K citations

  7. Colgate University

    Hamilton, United States

    4 h-index

    13 publications

    515 citations

  8. Inserm

    Paris, France

    3 h-index

    10 publications

    2.5K citations

1–8 of 123

Venues

  1. Nature

    6 publications · 1.7K citations

    6

    h-index

  2. Cell

    4 publications · 506 citations

    4

    h-index

  3. Developmental Biology

    4 publications · 295 citations

    4

    h-index

  4. Cell Reports

    3 publications · 323 citations

    3

    h-index

  5. Developmental Cell

    3 publications · 389 citations

    3

    h-index

1–5