Concepedia

Scaled Average Methodology

Scaled Average Methodology is a statistical approach in bioequivalence assessment that, as a member of the broader class of average bioequivalence methods, uniquely incorporates the within-subject variability of the reference product to scale the equivalence limits, thereby accommodating highly variable drugs or drug products.

15

Publications

560

Citations

47

Authors

24

Institutions

Publications per year

2017–2026

4

Parents

Publications

15

Scale and scope in drug development: unpacking the advantages of size in pharmaceutical research

Iain Cockburn, Rebecca Henderson · Journal of Health Economics · 2001 · 224 citations

, , +6

Limits for the Scaled Average Bioequivalence of Highly Variable Drugs and Drug Products

László Tóthfalusi, László Endrényi · Pharmaceutical Research · 2003 · 64 citations

, , +16

Regulatory and Study Conditions for the Determination of Bioequivalence of Highly Variable Drugs

László Endrényi, László Tóthfalusi · Journal of Pharmacy & Pharmaceutical Sciences · 2009 · 38 citations · Full text

, , +17

Novel Scaled Average Bioequivalence Limits Based on GMR and Variability Considerations

Vangelis Karalis, Mira Symillides, Panos Macheras · Pharmaceutical Research · 2004 · 32 citations

, , +13

Large variation existed in standardized mean difference estimates using different calculation methods in clinical trials

Yan Luo, Satoshi Funada, Kazufumi Yoshida et al. · Journal of Clinical Epidemiology · 2022 · 29 citations

, , +12

1–5 of 15

Authors

47

  1. LE
    László Endrényi

    University of Toronto, Canada

    5 publications · 158 citations

    5

    h-index

  2. LT
    László Tóthfalusi

    Semmelweis University, Hungary

    4 publications · 146 citations

    4

    h-index

  3. TA
    Toshi A. Furukawa

    Kyoto University, Japan

    1 publications · 29 citations

    1

    h-index

  4. KK
    Kwang‐il Kwon

    Chungnam National University, South Korea

    1 publications · 15 citations

    1

    h-index

  5. RH
    Rebecca Henderson

    Massachusetts Institute of Technology, United States

    1 publications · 224 citations

    1

    h-index

1–5 of 47

Institutions

24

  1. University of Toronto

    Toronto, Canada

    5 h-index

    5 publications

    158 citations

  2. Semmelweis University

    Budapest, Hungary

    4 h-index

    4 publications

    146 citations

  3. AGH University of Krakow

    Krakow, Poland

    1 h-index

    3 publications

    36 citations

  4. Pfizer (United States)

    New York, United States

    1 h-index

    1 publications

    13 citations

  5. Kyoto University

    Kyoto, Japan

    1 h-index

    5 publications

    145 citations

  6. University of Belgrade

    Belgrade, Serbia

    1 h-index

    5 publications

    80 citations

  7. Canada Research Chairs

    Ottawa, Canada

    1 h-index

    1 publications

    25 citations

  8. Amgen (United States)

    Thousand Oaks, United States

    1 h-index

    3 publications

    36 citations

1–8 of 24

Venues

  1. Pharmaceutical Research

    3 publications · 115 citations

    3

    h-index

  2. Journal of Pharmacy & Pharmaceutical Sciences

    JPPS · 2 publications · 57 citations

    2

    h-index

  3. Pharmaceutical Statistics

    1 publications · 13 citations

    1

    h-index

  4. Journal of Paleolimnology

    1 publications · 17 citations

    1

    h-index

  5. The AAPS Journal

    AAPSJ · 1 publications · 25 citations

    1

    h-index

1–5