Concepedia

Safe Harbor Integration

Safe Harbor Integration is a genome integration strategy that involves the targeted insertion of transgenes into genomic loci that are permissive for stable and consistent transgene expression without disrupting essential genes or regulatory elements.

11

Publications

627

Citations

96

Authors

25

Institutions

Publications per year

2017–2026

8

Variants

Safe Harbor Locus IntegrationSafe Harbor Site Integration

Parents

Publications

11

Efficient targeted integration directed by short homology in zebrafish and mammalian cells

Wesley A. Wierson, Jordan M. Welker, Maira P. Almeida et al. · eLife · 2020 · 165 citations · Full text

, , +17

Identification of “safe harbor†loci in indica rice genome by harnessing the property of zinc-finger nucleases to induce DNA damage and repair

Christian Cantos, Perigio B. Francisco, Kurniawan Rudi Trijatmiko et al. · Frontiers in Plant Science · 2014 · 94 citations · Full text

, , +17

Cas9-AAV6-engineered human mesenchymal stromal cells improved cutaneous wound healing in diabetic mice

Waracharee Srifa, Nina Kosaric, Alvaro Amorin et al. · Nature Communications · 2020 · 79 citations · Full text

, , +17

Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction

Hyunmin Cho, Pyung‐Hwan Kim, Hyun‐Kyung Chang et al. · Stem Cells Translational Medicine · 2017 · 60 citations · Full text

, , +17

Inducible HGF-secreting Human Umbilical Cord Blood-derived MSCs Produced via TALEN-mediated Genome Editing Promoted Angiogenesis

Hyun‐Kyung Chang, Pyung‐Hwan Kim, Hyunmin Cho et al. · Molecular Therapy · 2016 · 51 citations · Full text

, , +16

1–5 of 11

Authors

96

  1. HC
    Hyunmin Cho

    Seoul National University, South Korea

    3 publications · 155 citations

    3

    h-index

  2. JC
    Je‐Yoel Cho

    Seoul National University, South Korea

    3 publications · 155 citations

    3

    h-index

  3. MC
    Mincheol Choi

    Seoul National University, South Korea

    2 publications · 104 citations

    2

    h-index

  4. GJ
    Goo Jang

    Seoul National University, South Korea

    2 publications · 111 citations

    2

    h-index

  5. HC
    Hyun‐Kyung Chang

    Kyung Hee University, South Korea

    2 publications · 111 citations

    2

    h-index

1–5 of 96

Institutions

25

  1. Seoul National University

    Seoul, South Korea

    3 h-index

    30 publications

    1.6K citations

  2. Stanford University

    Stanford, United States

    2 h-index

    16 publications

    851 citations

  3. Stanford Medicine

    Stanford, United States

    2 h-index

    8 publications

    219 citations

  4. Agency for Science, Technology and Research

    Singapore, Singapore

    1 h-index

    3 publications

    42 citations

  5. Center for Agricultural Resources Research

    Fort Collins, United States

    1 h-index

    1 publications

    94 citations

  6. International Rice Research Institute

    Los Baños, Philippines

    1 h-index

    4 publications

    376 citations

  7. Mayo Clinic

    Rochester, United States

    1 h-index

    2 publications

    330 citations

  8. Nanyang Technological University

    Singapore, Singapore

    1 h-index

    6 publications

    84 citations

1–8 of 25

Venues

  1. G3 Genes Genomes Genetics

    2 publications · 81 citations

    2

    h-index

  2. Nature Communications

    1 publications · 79 citations

    1

    h-index

  3. Molecular Therapy

    1 publications · 51 citations

    1

    h-index

  4. eLife

    1 publications · 165 citations

    1

    h-index

  5. Molecular Therapy — Nucleic Acids

    1 publications · 44 citations

    1

    h-index

1–5