Root Effect
The Root Effect is a physiological phenomenon in hemoglobin physiology characterized by a marked reduction in hemoglobin's oxygen-carrying capacity under acidic conditions, distinguished from the Bohr effect by its inability to be fully reversed by increasing oxygen partial pressure.
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2017–2026
2
Variants
Root Phenomenon
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Root Effect Hemoglobin May Have Evolved to Enhance General Tissue Oxygen Delivery
Jodie L. Rummer, David J. McKenzie, Alessio Innocenti et al. · Science · 2013 · 175 citations · Full text
Nobutoshi Ito, Noboru H. Komiyama, G. Fermi · Journal of Molecular Biology · 1995 · 98 citations
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Institute of Protein Biochemistry
Naples, Italy
13 h-index
39 publications
1.3K citations

University of Naples Federico II
Naples, Italy
7 h-index
31 publications
1.3K citations
Institute of Biostructure and Bioimaging
Naples, Italy
6 h-index
20 publications
662 citations

University of British Columbia
Vancouver, Canada
5 h-index
12 publications
646 citations

Università di Camerino
Camerino, Italy
4 h-index
9 publications
219 citations

Aarhus University
Aarhus, Denmark
3 h-index
6 publications
273 citations
Istituto di Chimica Biomolecolare
Catania, Italy
3 h-index
11 publications
224 citations

University of Liverpool
Liverpool, United Kingdom
3 h-index
6 publications
144 citations
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9 publications · 475 citations
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JBC · 8 publications · 290 citations
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EJB · 4 publications · 102 citations
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4 publications · 86 citations
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PNAS · 2 publications · 63 citations
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