Concepedia

Rna Aptamer Binding

RNA Aptamer Binding is a molecular interaction mechanism in which an RNA aptamer, through its specific three-dimensional structure, selectively binds to a target ligand, thereby distinguishing itself from other RNA-ligand interactions by its high affinity and specificity evolved or selected in vitro.

878

Publications

56.9K

Citations

3.3K

Authors

932

Institutions

Publications per year

2017–2026

229

Parents

Publications

878

RNA Mimics of Green Fluorescent Protein

Jeremy S. Paige, Karen Wu, Samie R. Jaffrey · Science · 2011 · 1.4K citations · Full text

, , +15

Broccoli: Rapid Selection of an RNA Mimic of Green Fluorescent Protein by Fluorescence-Based Selection and Directed Evolution

Grigory S. Filonov, Jared D. Moon, Nina Svensen et al. · Journal of the American Chemical Society · 2014 · 786 citations · Full text

, , +15

2′-Fluoropyrimidine RNA-based Aptamers to the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF165)

Judy Ruckman, Louis S. Green, Jim Beeson et al. · Journal of Biological Chemistry · 1998 · 735 citations · Full text

, , +14

An mRNA structure that controls gene expression by binding FMN

Wade C. Winkler, Smadar Cohen‐Chalamish, Ronald R. Breaker · Proceedings of the National Academy of Sciences · 2002 · 712 citations · Full text

, , +17

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

Justin P. Dassie, Xiuying Liu, Gregory S. Thomas et al. · Nature Biotechnology · 2009 · 585 citations · Full text

, , +13

1–5 of 878

Authors

3.3K

  1. BA
    Bruce A. Sullenger

    Duke Medical Center, United States

    27 publications · 2.6K citations

    23

    h-index

  2. AD
    Andrew D. Ellington

    The University of Texas at Austin, United States

    26 publications · 2K citations

    23

    h-index

  3. DH
    Donald H. Burke

    University of Missouri, United States

    18 publications · 863 citations

    18

    h-index

  4. JT
    Jean‐Jacques Toulmé

    Inserm, France

    20 publications · 847 citations

    17

    h-index

  5. RR
    Ronald R. Breaker

    Yale University, United States

    16 publications · 2.3K citations

    16

    h-index

1–5 of 3.3K

Institutions

932

  1. Duke Medical Center

    Durham, United States

    24 h-index

    174 publications

    16.3K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    24 h-index

    98 publications

    6.1K citations

  3. Dankook University

    Jukjeon-dong, South Korea

    23 h-index

    116 publications

    5.8K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    23 h-index

    46 publications

    4.8K citations

  5. National Institute of Advanced Industrial Science and Technology

    Tsukuba, Japan

    23 h-index

    100 publications

    5.8K citations

  6. Inserm

    Paris, France

    22 h-index

    87 publications

    4K citations

  7. Duke University

    Durham, United States

    20 h-index

    83 publications

    6.2K citations

  8. Duke University Hospital

    Durham, United States

    20 h-index

    94 publications

    8.8K citations

1–8 of 932

Venues

  1. Nucleic Acids Research

    97 publications · 7.1K citations

    54

    h-index

  2. RNA

    50 publications · 3.2K citations

    35

    h-index

  3. Biochemistry

    41 publications · 2.2K citations

    30

    h-index

  4. Journal of the American Chemical Society

    JACS · 28 publications · 3.4K citations

    26

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 28 publications · 1.4K citations

    23

    h-index

1–5