Concepedia

Ring Size Effects

Ring Size Effects is a structural determinant in macrocyclic drug design that characterizes the influence of the number of atoms in the macrocyclic ring on conformational stability, target binding affinity, and pharmacokinetic properties.

648

Publications

28.6K

Citations

2.5K

Authors

617

Institutions

Publications per year

2017–2026

96

Parents

Publications

648

The Mayer bond order as a tool in inorganic chemistry†

Adam J. Bridgeman, Germán Cavigliasso, Luke Ireland et al. · Journal of the Chemical Society Dalton Transactions · 2001 · 606 citations

, , +16

Aromatic π-Stacking in Solution as Revealed through the Aggregation of Phenylacetylene Macrocycles

Ashok S. Shetty, Jinshan Zhang, Jeffrey S. Moore · Journal of the American Chemical Society · 1996 · 426 citations

, , +16

Human Serum Paraoxonase (pon1) Isozymes Q and R Hydrolyze Lactones and Cyclic Carbonate Esters

Scott S. Billecke, Dragomir Draganov, Raymond E. Counsell et al. · Drug Metabolism and Disposition · 2000 · 400 citations

, , +11

The Sting of the Scorpion: A Metallaboratrane

Anthony F. Hill, Gareth R. Owen, Andrew J. P. White et al. · Angewandte Chemie International Edition · 1999 · 351 citations · Full text

, , +8

The Role of Ring Strain on the Ease of Ring Closure of Bifunctional Chain Molecules

Carlo Galli, Luigi Mandolini · European Journal of Organic Chemistry · 2000 · 350 citations

, , +9

1–5 of 648

Authors

2.5K

  1. EK
    Erich Kleinpeter

    University of Potsdam, Germany

    6 publications · 119 citations

    6

    h-index

  2. MK
    Mutsuo Kodama

    Ibaraki University, Japan

    5 publications · 226 citations

    5

    h-index

  3. EK
    Eiichi Kimura

    Hiroshima University, Japan

    5 publications · 226 citations

    5

    h-index

  4. JW
    James W. Wilt

    Loyola University Chicago, United States

    5 publications · 88 citations

    5

    h-index

  5. GA
    Gregory A. Solan

    University of Leicester, United Kingdom

    4 publications · 113 citations

    4

    h-index

1–5 of 2.5K

Institutions

617

  1. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    52 publications

    1.8K citations

  2. Chinese Academy of Sciences

    Beijing, China

    11 h-index

    46 publications

    1.6K citations

  3. University of California, Los Angeles

    Los Angeles, United States

    8 h-index

    18 publications

    1.7K citations

  4. Institute of Chemistry

    Beijing, China

    7 h-index

    33 publications

    957 citations

  5. The University of Osaka

    Osaka, Japan

    7 h-index

    15 publications

    853 citations

  6. University of Michigan

    Ann Arbor, United States

    7 h-index

    28 publications

    1.7K citations

  7. University of Kansas

    Lawrence, United States

    6 h-index

    26 publications

    740 citations

  8. Kyoto University

    Kyoto, Japan

    6 h-index

    16 publications

    664 citations

1–8 of 617

Venues

  1. Journal of the American Chemical Society

    JACS · 69 publications · 4.5K citations

    35

    h-index

  2. The Journal of Organic Chemistry

    JOC · 53 publications · 1.6K citations

    25

    h-index

  3. Inorganic Chemistry

    33 publications · 1.2K citations

    22

    h-index

  4. Journal of Medicinal Chemistry

    23 publications · 1.3K citations

    21

    h-index

  5. Organometallics

    21 publications · 931 citations

    18

    h-index

1–5