Concepedia

Replication Protein A Function

Replication Protein a Function is a molecular mechanism within the DNA metabolism framework that specifically mediates single-stranded DNA binding during nucleotide excision repair and replication stress response, thereby stabilizing replication forks and facilitating DNA damage recognition and repair factor recruitment.

456

Publications

38.2K

Citations

1.7K

Authors

534

Institutions

Publications per year

2017–2026

65

Variants

Rpa Function

Parents

Publications

456

Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

Lee Zou, Stephen J. Elledge · Science · 2003 · 2.7K citations

, , +17

Recombinant replication protein A: expression, complex formation, and functional characterization

Leigh A. Henricksen, Christopher B. Umbricht, Marc S. Wold · Journal of Biological Chemistry · 1994 · 616 citations · Full text

, , +17

Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A

James H. New, Tomohiko Sugiyama, Elena Zaitseva et al. · Nature · 1998 · 583 citations

, , +14

Function of Yeast Rad52 Protein as a Mediator between Replication Protein A and the Rad51 Recombinase

Patrick Sung · Journal of Biological Chemistry · 1997 · 559 citations · Full text

, , +16

Inhibition of Human Chk1 Causes Increased Initiation of DNA Replication, Phosphorylation of ATR Targets, and DNA Breakage

Randi G. Syljuåsen, Claus Storgaard Sørensen, Lasse Tengbjerg Hansen et al. · Molecular and Cellular Biology · 2005 · 553 citations · Full text

, , +17

1–5 of 456

Authors

1.7K

  1. MS
    Marc S. Wold

    University of Iowa, United States

    42 publications · 4.8K citations

    33

    h-index

  2. HN
    Heinz‐Peter Nasheuer

    Ollscoil na Gaillimhe – University of Galway, Ireland

    17 publications · 550 citations

    16

    h-index

  3. OI
    Olga I. Lavrik

    Institute of Chemical Biology and Fundamental Medicine, Russia

    13 publications · 443 citations

    12

    h-index

  4. JJ
    John J. Turchi

    Wright State University, United States

    12 publications · 821 citations

    12

    h-index

  5. TJ
    Thomas J. Kelly

    Johns Hopkins University, United States

    11 publications · 1.8K citations

    11

    h-index

1–5 of 1.7K

Institutions

534

  1. University of Iowa

    Iowa City, United States

    31 h-index

    98 publications

    9.9K citations

  2. Vanderbilt University

    Nashville, United States

    20 h-index

    70 publications

    5.3K citations

  3. University of Zurich

    Zurich, Switzerland

    16 h-index

    61 publications

    3.8K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    42 publications

    1.8K citations

  5. Johns Hopkins University

    Baltimore, United States

    15 h-index

    45 publications

    6.6K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    15 h-index

    35 publications

    8.4K citations

  7. National Institutes of Health

    Bethesda, United States

    14 h-index

    48 publications

    5.4K citations

  8. Johns Hopkins Medicine

    Baltimore, United States

    12 h-index

    36 publications

    5.6K citations

1–8 of 534

Venues

  1. Journal of Biological Chemistry

    JBC · 101 publications · 9.2K citations

    56

    h-index

  2. Nucleic Acids Research

    68 publications · 3.7K citations

    35

    h-index

  3. Molecular and Cellular Biology

    MCB · 37 publications · 4.3K citations

    30

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 33 publications · 3.4K citations

    28

    h-index

  5. Biochemistry

    26 publications · 1.7K citations

    21

    h-index

1–5