Concepedia

Replication Checkpoint Mutants

Replication Checkpoint Mutants is a genetic construct that refers to a strain or cell variant with specific mutations in genes essential for the activation or maintenance of the replication checkpoint, thereby impairing the cell's ability to coordinate DNA replication with cell cycle progression in response to replication stress.

76

Publications

5.6K

Citations

314

Authors

128

Institutions

Publications per year

2017–2026

4

Parents

Publications

76

Fork Reversal and ssDNA Accumulation at Stalled Replication Forks Owing to Checkpoint Defects

José M. Sogo, Massimo Lopes, Marco Foiani · Science · 2002 · 821 citations

, , +17

Regulation of <i>RAD53</i> by the <i>ATM</i> -Like Kinases <i>MEC1</i> and <i>TEL1</i> in Yeast Cell Cycle Checkpoint Pathways

Yolanda Sánchez, Brian Desany, William J. Jones et al. · Science · 1996 · 591 citations

, , +17

The Replication Checkpoint Protects Fork Stability by Releasing Transcribed Genes from Nuclear Pores

Rodrigo Bermejo, Thelma Capra, Rachel Jossen et al. · Cell · 2011 · 215 citations · Full text

, , +17

DNA Damage and Replication Checkpoints in Fission Yeast Require Nuclear Exclusion of the Cdc25 Phosphatase via 14-3-3 Binding

Yan Zeng, Helen Piwnica‐Worms · Molecular and Cellular Biology · 1999 · 157 citations

, , +17

Suppression of genome instability by redundant S-phase checkpoint pathways in <i>Saccharomyces</i> <i>cerevisiae</i>

Kyungjae Myung, Richard D. Kolodner · Proceedings of the National Academy of Sciences · 2002 · 145 citations · Full text

, , +17

1–5 of 76

Authors

314

  1. PR
    Paul Russell

    Scripps Research Institute, United States

    4 publications · 338 citations

    4

    h-index

  2. KS
    Katsuhiko Shirahige

    The University of Tokyo, Japan

    3 publications · 321 citations

    3

    h-index

  3. JA
    Joel A. Huberman

    Roswell Park Comprehensive Cancer Center, United States

    3 publications · 101 citations

    3

    h-index

  4. JL
    Janet Leatherwood

    Stony Brook University, United States

    3 publications · 77 citations

    3

    h-index

  5. AK
    Amnon Koren

    Cornell University, United States

    2 publications · 198 citations

    2

    h-index

1–5 of 314

Institutions

128

  1. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    28 publications

    2K citations

  2. Scripps Research Institute

    San Diego, United States

    4 h-index

    8 publications

    785 citations

  3. Roswell Park Comprehensive Cancer Center

    Buffalo, United States

    4 h-index

    10 publications

    392 citations

  4. University of Washington

    Seattle, United States

    4 h-index

    10 publications

    476 citations

  5. The University of Osaka

    Osaka, Japan

    3 h-index

    13 publications

    561 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    8 publications

    3.7K citations

  7. University of Sussex

    Brighton, United Kingdom

    3 h-index

    3 publications

    211 citations

  8. Stony Brook University

    Stony Brook, United States

    3 h-index

    9 publications

    243 citations

1–8 of 128

Venues

  1. Molecular and Cellular Biology

    MCB · 13 publications · 939 citations

    13

    h-index

  2. Genetics

    10 publications · 378 citations

    10

    h-index

  3. PLoS Genetics

    4 publications · 132 citations

    4

    h-index

  4. Molecular Biology of the Cell

    MBC · 3 publications · 169 citations

    3

    h-index

  5. Journal of Cell Science

    3 publications · 191 citations

    3

    h-index

1–5