Concepedia

Replication Bubble Formation

Replication Bubble Formation is a topological event in DNA replication initiation wherein localized unwinding of the double helix by initiator proteins generates a discrete region of single-stranded DNA bounded by two opposing replication forks, distinguishing it from other DNA structural transitions by its specific association with bidirectional replication origin activation.

30

Publications

1.5K

Citations

92

Authors

35

Institutions

Publications per year

2017–2026

2

Parents

Publications

30

Multiple replication origins are used during Drosophila chorion gene amplification.

Margarete M. S. Heck, Allan C. Spradling · The Journal of Cell Biology · 1990 · 167 citations · Full text

, , +12

Initiation of DNA replication in the dihydrofolate reductase locus is confined to the early S period in CHO cells synchronized with the plant amino acid mimosine.

Peter A. Dijkwel, Joyce L. Hamlin · Molecular and Cellular Biology · 1992 · 129 citations

, , +12

Three domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen

Ramon Parsons, Mary E. Anderson, P Tegtmeyer · Journal of Virology · 1990 · 125 citations · Full text

, , +15

Electron microscopic study of Saccharomyces cerevisiae rDNA chromatin replication.

Linda D. Saffer, O. L. Miller · Molecular and Cellular Biology · 1986 · 112 citations · Full text

, , +10

Autonomous replication of plasmids bearing monkey DNA origin-enriched sequences.

Lori Frappier, Maria Zannis‐Hadjopoulos · Proceedings of the National Academy of Sciences · 1987 · 83 citations · Full text

, , +13

1–5 of 30

Authors

92

  1. JL
    Joyce L. Hamlin

    University of Virginia, United States

    4 publications · 251 citations

    4

    h-index

  2. OL
    O. L. Miller

    Oak Ridge National Laboratory, United States

    3 publications · 173 citations

    3

    h-index

  3. ME
    Mary E. Anderson

    Stony Brook University, United States

    3 publications · 182 citations

    3

    h-index

  4. PT
    P Tegtmeyer

    Stony Brook University, United States

    3 publications · 182 citations

    3

    h-index

  5. PA
    Pieter A. Dijkwel

    University of Virginia, United States

    2 publications · 69 citations

    2

    h-index

1–5 of 92

Institutions

35

  1. University of Virginia

    Charlottesville, United States

    8 h-index

    21 publications

    1.1K citations

  2. Stony Brook University

    Stony Brook, United States

    3 h-index

    12 publications

    687 citations

  3. Centro de Investigaciones Biológicas Margarita Salas

    Madrid, Spain

    2 h-index

    7 publications

    251 citations

  4. Carnegie Observatories

    Pasadena, United States

    1 h-index

    2 publications

    334 citations

  5. Brown University

    Providence, United States

    1 h-index

    2 publications

    86 citations

  6. Norwegian Cancer Society

    Oslo, Norway

    1 h-index

    4 publications

    184 citations

  7. Delft University of Technology

    Delft, The Netherlands

    1 h-index

    5 publications

    380 citations

  8. Imperial College London

    London, United Kingdom

    1 h-index

    4 publications

    48 citations

1–8 of 35

Venues

  1. Molecular and Cellular Biology

    MCB · 10 publications · 530 citations

    10

    h-index

  2. Journal of Virology

    JVI · 4 publications · 215 citations

    4

    h-index

  3. Nucleic Acids Research

    3 publications · 157 citations

    3

    h-index

  4. Journal of Biological Chemistry

    JBC · 2 publications · 78 citations

    2

    h-index

  5. 2

    h-index

1–5