Concepedia

Release Factor Function

Release Factor Function is a molecular mechanism in the translation termination process that belongs to the class of protein synthesis factors, specifically distinguished by its role in recognizing stop codons on the mRNA and catalyzing the hydrolysis of the peptidyl-tRNA bond to release the newly synthesized polypeptide from the ribosome.

212

Publications

15K

Citations

679

Authors

204

Institutions

Publications per year

2017–2026

21

Parents

Publications

212

Genomically Recoded Organisms Expand Biological Functions

Alexis J. Rovner, Daniel B. Goodman, Hans R. Aerni et al. · Science · 2013 · 884 citations · Full text

, , +17

The Crystal Structure of Human Eukaryotic Release Factor eRF1—Mechanism of Stop Codon Recognition and Peptidyl-tRNA Hydrolysis

Haiwei Song, Pierre Mugnier, Amit Kumar Das et al. · Cell · 2000 · 465 citations · Full text

, , +15

A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor

L Iu Frolova, Xavier Le Goff, Hanne H. Rasmussen et al. · Nature · 1994 · 412 citations

, , +10

Release factors differing in specificity for terminator codons.

Edward M. Scolnick, Richard K. Tompkins, T. Caskey et al. · Proceedings of the National Academy of Sciences · 1968 · 380 citations · Full text

, , +11

Mutations in the highly conserved GGQ motif of class 1 polypeptide release factors abolish ability of human eRF1 to trigger peptidyl-tRNA hydrolysis

Ludmila Frolova, Ruslan Tsivkovskii, G. F. Sivolobova et al. · RNA · 1999 · 359 citations · Full text

, , +17

1–5 of 212

Authors

679

  1. WP
    Warren P. Tate

    University of Otago, New Zealand

    27 publications · 1.1K citations

    21

    h-index

  2. LL
    Lev L. Kisselev

    Engelhardt Institute of Molecular Biology, Russia

    18 publications · 2.1K citations

    18

    h-index

  3. CT
    C. Thomas Caskey

    Baylor College of Medicine, United States

    15 publications · 1.2K citations

    15

    h-index

  4. YN
    Yoshikazu Nakamura

    The University of Tokyo, Japan

    12 publications · 832 citations

    12

    h-index

  5. LF
    Ludmila Frolova

    Engelhardt Institute of Molecular Biology, Russia

    11 publications · 1.1K citations

    11

    h-index

1–5 of 679

Institutions

204

  1. University of Otago

    Dunedin, New Zealand

    19 h-index

    87 publications

    3.1K citations

  2. Engelhardt Institute of Molecular Biology

    Moscow, Russia

    19 h-index

    54 publications

    5.7K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    43 publications

    4K citations

  4. The University of Tokyo

    Tokyo, Japan

    12 h-index

    36 publications

    3.5K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    35 publications

    2.8K citations

  6. Uppsala University

    Uppsala, Sweden

    9 h-index

    23 publications

    2.1K citations

  7. Tokyo University of Science

    Tokyo, Japan

    9 h-index

    25 publications

    2.5K citations

  8. Max Planck Institute for Molecular Genetics

    Berlin, Germany

    8 h-index

    25 publications

    772 citations

1–8 of 204

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 24 publications · 2.2K citations

    23

    h-index

  2. Journal of Biological Chemistry

    JBC · 26 publications · 1.1K citations

    21

    h-index

  3. Nucleic Acids Research

    16 publications · 722 citations

    14

    h-index

  4. Journal of Bacteriology

    JB · 15 publications · 623 citations

    14

    h-index

  5. Journal of Molecular Biology

    JMB · 12 publications · 752 citations

    12

    h-index

1–5