Concepedia

Reference Dose Derivation

Reference Dose Derivation is a scientific method within dose-response assessment that quantitatively estimates the maximum acceptable daily exposure to a chemical substance over a lifetime, distinguished by its reliance on uncertainty factors to extrapolate from observed toxicity data to a safe human exposure level.

50

Publications

3.6K

Citations

232

Authors

83

Institutions

Publications per year

2017–2026

13

Parents

Publications

50

Reference dose (RfD): Description and use in health risk assessments

Donald Grove Barnes, Michael L. Dourson, Michael L. Dourson et al. · Regulatory Toxicology and Pharmacology · 1988 · 822 citations

, , +13

Update: use of the benchmark dose approach in risk assessment

Diane Benford, Michael Jeger, Katrine Helle Knutsen et al. · EFSA Journal · 2017 · 508 citations · Full text

, , +15

Neonicotinoid Residues in Fruits and Vegetables: An Integrated Dietary Exposure Assessment Approach

Chensheng Lu, Chi-Hsuan Chang, Cynthia Palmer et al. · Environmental Science & Technology · 2018 · 273 citations

, , +17

Guidance on the use of the benchmark dose approach in risk assessment

Simon J. More, Vasileios Bampidis, Diane Benford et al. · EFSA Journal · 2022 · 210 citations · Full text

, , +16

Benchmark Dose Workshop: Criteria for Use of a Benchmark Dose to Estimate a Reference Dose

Donald Grove Barnes, G. P. Daston, John S. Evans et al. · Regulatory Toxicology and Pharmacology · 1995 · 135 citations

, , +14

1–5 of 50

Authors

232

  1. ML
    Michael L. Dourson

    Impact Assessment, United States

    5 publications · 1.8K citations

    4

    h-index

  2. DB
    Diane Benford

    Lille Inflammation Research International Center, France

    2 publications · 718 citations

    2

    h-index

  3. MA
    Marc Aerts

    Hasselt University, Belgium

    2 publications · 718 citations

    2

    h-index

  4. VS
    Virunya S. Bhat

    National Sanitation Foundation International, United States

    2 publications · 37 citations

    2

    h-index

  5. DW
    David W. Gaylor

    National Center for Toxicological Research, United States

    2 publications · 57 citations

    2

    h-index

1–5 of 232

Institutions

83

  1. Environmental Protection Agency

    Washington, United States

    6 h-index

    22 publications

    3.5K citations

  2. National Center for Environmental Assessment (EPA)

    Cincinnati, United States

    5 h-index

    13 publications

    857 citations

  3. Harvard University

    Cambridge, United States

    3 h-index

    12 publications

    1.9K citations

  4. United States Food and Drug Administration

    Silver Spring, United States

    3 h-index

    4 publications

    98 citations

  5. National Center for Toxicological Research

    Pine Bluff, United States

    3 h-index

    5 publications

    111 citations

  6. Downtown Women's Health Care

    Denver, United States

    3 h-index

    5 publications

    80 citations

  7. Environmental Protection Agency

    Wexford, Ireland

    2 h-index

    3 publications

    1.8K citations

  8. Exponent (United States)

    Menlo Park, United States

    2 h-index

    3 publications

    31 citations

1–8 of 83

Venues

  1. Regulatory Toxicology and Pharmacology

    RTP · 10 publications · 1.1K citations

    10

    h-index

  2. Radiation Protection Dosimetry

    8 publications · 227 citations

    8

    h-index

  3. Medical Physics

    5 publications · 218 citations

    5

    h-index

  4. Risk Analysis

    4 publications · 161 citations

    4

    h-index

  5. EFSA Journal

    3 publications · 816 citations

    3

    h-index

1–5