Concepedia

Rectal Pharmacokinetics

Rectal Pharmacokinetics is a pharmacokinetic process model that characterizes the absorption, distribution, metabolism, and elimination of drugs administered via the rectal route, distinguishing itself from other routes by accounting for the unique anatomical, physiological, and biochemical features of the rectal milieu influencing systemic drug disposition.

130

Publications

3.8K

Citations

411

Authors

128

Institutions

Publications per year

2017–2026

1

Parents

Publications

130

Comparative clinical pharmacokinetics of single doses of sumatriptan following subcutaneous, oral, rectal and intranasal administration

C. Duquesnoy, Julien Mamet, D. J. Sumner et al. · European Journal of Pharmaceutical Sciences · 1998 · 125 citations

, , +12

Pharmacokinetics and adverse-effect profile of rectally administered misoprostol in the third stage of labor

Raja B. Khan · Obstetrics and Gynecology · 2003 · 105 citations

, , +16

Rectal bioavailability of lidocaine in man: Partial avoidance of “first‐pass” metabolism

Albertus G. de Boer, D. D. Breimer, H. Mattie et al. · Clinical Pharmacology & Therapeutics · 1979 · 93 citations

, , +17

Comparative Oxycodone Pharmacokinetics in Humans After Intravenous, Oral, and Rectal Administration

Kim P. Leow, Maree T. Smith, J. A. Watt et al. · Therapeutic Drug Monitoring · 1992 · 89 citations

, , +15

Pharmacokinetics of ketoprofen following single oral, intramuscular and rectal doses and after repeated oral administration

Takashi Ishizaki, T. Sasaki, Toshiyuki Suganuma et al. · European Journal of Clinical Pharmacology · 1980 · 88 citations

, , +7

1–5 of 130

Authors

411

  1. TN
    Toshiaki Nishihata

    University of Kansas, United States

    13 publications · 384 citations

    11

    h-index

  2. FM
    Frits Moolenaar

    University of Groningen, Netherlands

    13 publications · 313 citations

    11

    h-index

  3. TH
    Takeru Higuchi

    University of Kansas, United States

    11 publications · 361 citations

    11

    h-index

  4. AG
    Albertus G. de Boer

    Leiden University, Netherlands

    11 publications · 282 citations

    10

    h-index

  5. JH
    J. Howard Rytting

    University of Kansas, United States

    10 publications · 342 citations

    10

    h-index

1–5 of 411

Institutions

128

  1. University of Kansas

    Lawrence, United States

    11 h-index

    41 publications

    1.4K citations

  2. Leiden University

    Leiden, The Netherlands

    11 h-index

    46 publications

    1.3K citations

  3. University of Groningen

    Groningen, The Netherlands

    7 h-index

    30 publications

    852 citations

  4. Vesuvius (United Kingdom)

    London, United Kingdom

    4 h-index

    13 publications

    216 citations

  5. Dialyse Centrum Groningen

    Groningen, The Netherlands

    4 h-index

    12 publications

    221 citations

  6. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    4 h-index

    8 publications

    221 citations

  7. University of Southern California

    Los Angeles, United States

    4 h-index

    7 publications

    207 citations

  8. University of Minnesota

    Minneapolis, United States

    3 h-index

    8 publications

    238 citations

1–8 of 128

Venues

  1. Journal of Pharmacy and Pharmacology

    JPP · 11 publications · 390 citations

    11

    h-index

  2. Journal of Pharmaceutical Sciences

    13 publications · 300 citations

    11

    h-index

  3. European Journal of Clinical Pharmacology

    9 publications · 323 citations

    9

    h-index

  4. International Journal of Pharmaceutics

    9 publications · 192 citations

    9

    h-index

  5. PubMed

    Repository · 8 publications · 127 citations

    8

    h-index

1–5