Concepedia

Receptor Binding Modulation

Receptor Binding Modulation is a biochemical strategy within bioisosteric design that entails the deliberate alteration of molecular interactions at a receptor site through structurally similar substituents to fine-tune affinity, efficacy, or selectivity of ligand-receptor binding.

633

Publications

34.6K

Citations

2.9K

Authors

737

Institutions

Publications per year

2017–2026

49

Parents

Publications

633

Intraoperative floppy iris syndrome associated with tamsulosin

David F. Chang, John Campbell · Journal of Cataract & Refractive Surgery · 2005 · 497 citations

, , +11

Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action.

Kelvin W. Gee, Michael B. Bolger, Roberta Dı́az Brinton et al. · Journal of Pharmacology and Experimental Therapeutics · 1988 · 467 citations

, , +17

Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain

Carlo Colantuoni, J. Schwenker, Joseph McCarthy et al. · Neuroreport · 2001 · 466 citations

, , +17

Intraoperative floppy iris syndrome associated with tamsulosin

David F. Chang, John R. Campbell · Journal of Cataract & Refractive Surgery · 2005 · 393 citations

, , +11

In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-A congeners and derivatives via nuclear receptors

José-Manuel Molina-Molina, Esperanza Amaya, Marina Grimaldi et al. · Toxicology and Applied Pharmacology · 2013 · 366 citations · Full text

, , +17

1–5 of 633

Authors

2.9K

  1. SH
    Solomon H. Snyder

    Johns Hopkins University, United States

    7 publications · 643 citations

    7

    h-index

  2. GW
    Gavril W. Pasternak

    Memorial Sloan Kettering Cancer Center, United States

    5 publications · 458 citations

    5

    h-index

  3. BS
    Bruce S. McEwen

    Rockefeller University, United States

    5 publications · 570 citations

    5

    h-index

  4. KA
    Kenneth A. Jacobson

    National Institutes of Health, United States

    5 publications · 267 citations

    5

    h-index

  5. AE
    Allan E. Johnson

    Rockefeller University, United States

    5 publications · 283 citations

    5

    h-index

1–5 of 2.9K

Institutions

737

  1. National Institute of Mental Health

    Bethesda, United States

    15 h-index

    45 publications

    2.9K citations

  2. National Institutes of Health

    Bethesda, United States

    14 h-index

    45 publications

    2.5K citations

  3. Johns Hopkins University

    Baltimore, United States

    11 h-index

    32 publications

    2.9K citations

  4. Karolinska Institutet

    Stockholm, Sweden

    11 h-index

    32 publications

    1.9K citations

  5. Rockefeller University

    New York, United States

    11 h-index

    36 publications

    3.8K citations

  6. Inserm

    Paris, France

    10 h-index

    24 publications

    1.7K citations

  7. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    10 h-index

    43 publications

    2K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    26 publications

    1K citations

1–8 of 737

Venues

  1. European Journal of Pharmacology

    EJP · 36 publications · 1.2K citations

    22

    h-index

  2. Journal of Medicinal Chemistry

    27 publications · 1K citations

    22

    h-index

  3. Molecular Pharmacology

    26 publications · 1.2K citations

    20

    h-index

  4. 19

    h-index

  5. Endocrinology

    25 publications · 1.7K citations

    19

    h-index

1–5