Concepedia

Rasburicase Therapy

Rasburicase Therapy is a pharmacological intervention that utilizes the recombinant uric acid oxidase enzyme rasburicase to rapidly degrade uric acid and prevent its accumulation during tumor lysis syndrome, thereby mitigating the risk of acute kidney injury and metabolic complications in high-risk patients.

92

Publications

5K

Citations

483

Authors

226

Institutions

Publications per year

2017–2026

13

Parents

Publications

92

A randomized comparison between rasburicase and allopurinol in children with lymphoma or leukemia at high risk for tumor lysis

Stanton Goldman, John S. Holcenberg, Jerry Z. Finklestein et al. · Blood · 2001 · 476 citations · Full text

, , +13

Recombinant Urate Oxidase for the Prophylaxis or Treatment of Hyperuricemia in Patients With Leukemia or Lymphoma

Ching‐Hon Pui, Hazem H. Mahmoud, Joseph M. Wiley et al. · Journal of Clinical Oncology · 2001 · 365 citations

, , +13

Efficacy and Safety of Rasburicase (recombinant urate oxidase) for the Prevention and Treatment of Hyperuricemia During Induction Chemotherapy of Aggressive Non-Hodgkin’s Lymphoma: Results of the GRAAL1 (Groupe d’Etude des Lymphomes de l’Adulte Trial on Rasburicase Activity in Adult Lymphoma) Study

Bertrand Coiffier, Nicolas Mounier, Serge Bologna et al. · Journal of Clinical Oncology · 2003 · 240 citations

, , +14

Control of Plasma Uric Acid in Adults at Risk for Tumor Lysis Syndrome: Efficacy and Safety of Rasburicase Alone and Rasburicase Followed by Allopurinol Compared With Allopurinol Alone—Results of a Multicenter Phase III Study

Jörge E. Cortes, Joseph O. Moore, Richard T. Maziarz et al. · Journal of Clinical Oncology · 2010 · 198 citations

, , +13

Efficacy and safety of rasburicase, a recombinant urate oxidase (Elitek™), in the management of malignancy-associated hyperuricemia in pediatric and adult patients: final results of a multicenter compassionate use trial

Sima Jeha, H. Kantarjian, David Irwin et al. · Leukemia · 2004 · 181 citations

, , +7

1–5 of 92

Authors

483

  1. MV
    Mary V. Relling

    St. Jude Children's Research Hospital, United States

    4 publications · 580 citations

    4

    h-index

  2. MS
    Mitchell S. Cairo

    New York Medical College, United States

    4 publications · 593 citations

    4

    h-index

  3. SJ
    Sima Jeha

    St. Jude Children's Research Hospital, United States

    3 publications · 343 citations

    3

    h-index

  4. CE
    Cyrine E. Haidar

    St. Jude Children's Research Hospital, United States

    3 publications · 215 citations

    3

    h-index

  5. BM
    Bruce M. Camitta

    Medical College of Wisconsin, United States

    3 publications · 695 citations

    3

    h-index

1–5 of 483

Institutions

226

  1. St. Jude Children's Research Hospital

    Memphis, United States

    6 h-index

    33 publications

    5.2K citations

  2. Université Paris Cité

    Paris, France

    4 h-index

    10 publications

    294 citations

  3. The University of Texas MD Anderson Cancer Center

    Houston, United States

    3 h-index

    5 publications

    609 citations

  4. University of Maryland, Baltimore

    Baltimore, United States

    3 h-index

    8 publications

    251 citations

  5. Emma Kinderziekenhuis

    Amsterdam, Netherlands

    2 h-index

    2 publications

    230 citations

  6. Ghent University Hospital

    Ghent, Belgium

    2 h-index

    12 publications

    336 citations

  7. Medical College of Wisconsin

    Milwaukee, United States

    2 h-index

    2 publications

    194 citations

  8. Heidelberg University

    Heidelberg, Germany

    2 h-index

    11 publications

    540 citations

1–8 of 226

Venues

  1. Annals of Pharmacotherapy

    6 publications · 271 citations

    6

    h-index

  2. Journal of Oncology Pharmacy Practice

    6 publications · 138 citations

    6

    h-index

  3. PubMed

    Repository · 5 publications · 194 citations

    5

    h-index

  4. 5

    h-index

  5. Pediatric Nephrology

    3 publications · 88 citations

    3

    h-index

1–5