Concepedia

Random Integration Design

Random Integration Design is a transgene delivery strategy belonging to the class of integration-based genetic engineering methods, distinguished by its reliance on non-targeted insertion of transgenic material into host genomes via stochastic recombination events.

4

Publications

150

Citations

17

Authors

7

Institutions

Publications per year

2017–2026

2

Parents

Publications

4

Strategic deployment of C <scp>HO</scp> expression platforms to deliver Pfizer's Monoclonal Antibody Portfolio

John J. Scarcelli, Tanya Q. Shang, Tim Iskra et al. · Biotechnology Progress · 2017 · 48 citations

, , +16

Worldwide Trends in the Use of Animals in Research: The Contribution of Genetically-modified Animal Models

Elisabeth Ormandy, Catherine A. Schuppli, Daniel M. Weary · Alternatives to Laboratory Animals · 2009 · 41 citations

, , +14

Predicting favorable landing pads for targeted integrations in Chinese hamster ovary cell lines by learning stability characteristics from random transgene integrations

Heena Dhiman, Marguerite Campbell, Michael Melcher et al. · Computational and Structural Biotechnology Journal · 2020 · 37 citations · Full text

, , +14

DNA topoisomerase II inhibitors enhance random integration of transfected vectors into human chromosomes

Katsumichi Fujimaki, Yasuaki Aratani, Shin Fujisawa et al. · Somatic Cell and Molecular Genetics · 1996 · 24 citations

, , +16

1–4 of 4

Authors

17

  1. TQ
    Tanya Q. Shang

    University of Washington, United States

    1 publications · 48 citations

    1

    h-index

  2. EO
    Elisabeth Ormandy

    Scottish Agricultural Science Agency, United Kingdom

    1 publications · 41 citations

    1

    h-index

  3. CA
    Catherine A. Schuppli

    University of British Columbia, Canada

    1 publications · 41 citations

    1

    h-index

  4. HD
    Heena Dhiman

    BOKU University, Austria

    1 publications · 37 citations

    1

    h-index

  5. MJ
    Martin J. Allen

    Yale University, United States

    1 publications · 48 citations

    1

    h-index

1–5 of 17

Institutions

7

  1. Austrian Centre of Industrial Biotechnology (Austria)

    Graz, Austria

    1 h-index

    2 publications

    74 citations

  2. Yokohama City University

    Yokohama, Japan

    1 h-index

    6 publications

    144 citations

  3. Pfizer (United States)

    New York, United States

    1 h-index

    4 publications

    192 citations

  4. University of British Columbia

    Vancouver, Canada

    1 h-index

    3 publications

    123 citations

  5. Kihara Institute for Biological Research

    Yokohama, Japan

    1 h-index

    3 publications

    72 citations

  6. BOKU University

    Vienna, Austria

    1 h-index

    3 publications

    111 citations

  7. Janssen (United States)

    Hopewell, United States

    1 h-index

    2 publications

    74 citations

1–7 of 7

Venues

  1. 1

    h-index

  2. Biotechnology Progress

    1 publications · 48 citations

    1

    h-index

  3. Somatic Cell and Molecular Genetics

    1 publications · 24 citations

    1

    h-index

  4. Alternatives to Laboratory Animals

    1 publications · 41 citations

    1

    h-index

1–4