Concepedia

Rag2 Recombinase Complex

The RAG2 Recombinase Complex is a site-specific recombinase complex composed of the RAG1 and RAG2 proteins that catalyzes V(D)J recombination by recognizing recombination signal sequences and mediating DNA cleavage at immunoglobulin and T-cell receptor gene segments.

26

Publications

1.8K

Citations

138

Authors

74

Institutions

Publications per year

2017–2026

3

Parents

Publications

26

RAG2:GFP Knockin Mice Reveal Novel Aspects of RAG2 Expression in Primary and Peripheral Lymphoid Tissues

R. J. Monroe, Katherine J. Seidl, Frank H. Gaertner et al. · Immunity · 1999 · 167 citations · Full text

, , +14

Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex

Kuang Shen, Kacper B. Rogala, Hui‐Ting Chou et al. · Cell · 2019 · 137 citations · Full text

, , +9

Selective expression of RAG-2 in chicken B cells undergoing immunoglobulin gene conversion

Louise Carlson, Marjorie A. Oettinger, David G. Schatz et al. · Cell · 1991 · 128 citations · Full text

, , +16

Ubiquitylation of RAG-2 by Skp2-SCF Links Destruction of the V(D)J Recombinase to the Cell Cycle

Hao Jiang, Fu‐Chung Chang, Ashley E. Ross et al. · Molecular Cell · 2005 · 126 citations · Full text

, , +16

The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis

Isabelle Callebaut, Jean‐Paul Mornon · Cellular and Molecular Life Sciences · 1998 · 112 citations · Full text

, , +15

1–5 of 26

Authors

138

  1. DG
    David G. Schatz

    Yale University, United States

    4 publications · 263 citations

    4

    h-index

  2. PC
    Patrick C. Swanson

    CHI Health Creighton University Medical Center - Bergan Mercy, United States

    3 publications · 90 citations

    3

    h-index

  3. DB
    David B. Roth

    Baylor College of Medicine, United States

    2 publications · 78 citations

    2

    h-index

  4. JC
    Julie Chaumeil

    Centre National de la Recherche Scientifique, France

    2 publications · 103 citations

    2

    h-index

  5. LD
    Ludovic Deriano

    Institut Pasteur, France

    2 publications · 78 citations

    2

    h-index

1–5 of 138

Institutions

74

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    25 publications

    3.1K citations

  2. Harvard University

    Cambridge, United States

    5 h-index

    10 publications

    672 citations

  3. Massachusetts General Hospital

    Boston, United States

    4 h-index

    10 publications

    811 citations

  4. New York University

    New York, United States

    3 h-index

    13 publications

    560 citations

  5. CHI Health Creighton University Medical Center - Bergan Mercy

    Omaha, United States

    3 h-index

    8 publications

    212 citations

  6. Yale University

    New Haven, United States

    3 h-index

    5 publications

    222 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    3 publications

    262 citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    6 publications

    795 citations

1–8 of 74

Venues

  1. The EMBO Journal

    3 publications · 221 citations

    3

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 246 citations

    3

    h-index

  3. Molecular and Cellular Biology

    MCB · 2 publications · 105 citations

    2

    h-index

  4. Molecular Cell

    2 publications · 182 citations

    2

    h-index

  5. Cell

    2 publications · 265 citations

    2

    h-index

1–5