Concepedia

Quality Control Of Aberrant Transcripts

Quality Control of Aberrant Transcripts is a molecular surveillance mechanism that selectively targets and degrades aberrant messenger RNAs containing premature termination codons to prevent the accumulation of potentially deleterious truncated proteins.

18

Publications

925

Citations

79

Authors

45

Institutions

Publications per year

2017–2026

6

Parents

Publications

18

UPF1 is required for nonsense‐mediated mRNA decay (NMD) and RNAi in Arabidopsis

Luis Arciga‐Reyes, Lucie Wootton, Martin Kieffer et al. · The Plant Journal · 2006 · 199 citations

, , +14

TUT‐DIS3L2 is a mammalian surveillance pathway for aberrant structured non‐coding RNAs

Dmytro Ustianenko, Josef Pasulka, Zuzana Feketová et al. · The EMBO Journal · 2016 · 112 citations · Full text

, , +17

Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of ullrich disease fibroblasts

Fusako Usuki, Akio Yamashita, Isao Kashima et al. · Molecular Therapy · 2006 · 92 citations · Full text

, , +17

hnRNP L‐dependent protection of normal mRNAs from NMD subverts quality control in B cell lymphoma

Aparna Kishor, Zhiyun Ge, J. Robert Hogg · The EMBO Journal · 2018 · 78 citations · Full text

, , +17

A Quality Control Pathway That Down-regulates Aberrant T-cell Receptor (TCR) Transcripts by a Mechanism Requiring UPF2 and Translation

Jun Wang, Vita M. Vock, Shulin Li et al. · Journal of Biological Chemistry · 2002 · 75 citations · Full text

, , +17

1–5 of 18

Authors

79

  1. BD
    Brendan Davies

    University of Leeds, United Kingdom

    2 publications · 228 citations

    2

    h-index

  2. ZG
    Zhiyun Ge

    National Heart Lung and Blood Institute, United States

    2 publications · 105 citations

    2

    h-index

  3. MK
    Martin Kieffer

    University of Leeds, United Kingdom

    1 publications · 199 citations

    1

    h-index

  4. CM
    Christine Mosrin-Huaman

    Centre National de la Recherche Scientifique, France

    1 publications · 31 citations

    1

    h-index

  5. HH
    Henry Hudson

    1 publications · 43 citations

    1

    h-index

1–5 of 79

Institutions

45

  1. University of Warsaw

    Warsaw, Poland

    2 h-index

    4 publications

    107 citations

  2. University of Leeds

    Leeds, United Kingdom

    2 h-index

    6 publications

    684 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    6 publications

    187 citations

  4. National Institutes of Health

    Bethesda, United States

    2 h-index

    7 publications

    322 citations

  5. University Hospital Frankfurt

    Frankfurt am Main, Germany

    1 h-index

    1 publications

    20 citations

  6. Kagoshima University

    Kagoshima, Japan

    1 h-index

    2 publications

    184 citations

  7. University of Milan

    Milan, Italy

    1 h-index

    2 publications

    40 citations

  8. RIKEN Center for Computational Science

    Kobe, Japan

    1 h-index

    1 publications

    27 citations

1–8 of 45

Venues

  1. Journal of Biological Chemistry

    JBC · 3 publications · 119 citations

    3

    h-index

  2. The Plant Journal

    2 publications · 224 citations

    2

    h-index

  3. The EMBO Journal

    2 publications · 190 citations

    2

    h-index

  4. Nucleic Acids Research

    2 publications · 60 citations

    2

    h-index

  5. Molecular Microbiology

    1 publications · 27 citations

    1

    h-index

1–5