Concepedia

Proviral Silencing

Proviral silencing is a molecular regulatory mechanism, within the broader class of epigenetic gene regulation processes, that specifically involves the suppression of viral gene expression from integrated proviral DNA through host-mediated epigenetic modifications such as DNA methylation, histone deacetylation, and chromatin remodeling, thereby maintaining viral latency.

131

Publications

9.2K

Citations

816

Authors

299

Institutions

Publications per year

2017–2026

40

Parents

Publications

131

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

Toshiyuki Matsui, Danny Leung, Hiroki Miyashita et al. · Nature · 2010 · 822 citations · Full text

, , +16

TRIM28 Mediates Primer Binding Site-Targeted Silencing of Murine Leukemia Virus in Embryonic Cells

Daniel Wolf, Stephen P. Goff · Cell · 2007 · 345 citations

, , +13

CpG Methylation Controls Reactivation of HIV from Latency

Jana Blažková, Kateřina Trejbalová, Françoise Gondois‐Rey et al. · PLoS Pathogens · 2009 · 327 citations · Full text

, , +17

Epigenetic Silencing of Human Immunodeficiency Virus (HIV) Transcription by Formation of Restrictive Chromatin Structures at the Viral Long Terminal Repeat Drives the Progressive Entry of HIV into Latency

Richard D. Pearson, Young Kyeung Kim, Joseph Hokello et al. · Journal of Virology · 2008 · 307 citations · Full text

, , +17

Epigenetic Silencing of HIV-1 by the Histone H3 Lysine 27 Methyltransferase Enhancer of Zeste 2

Julia H. Friedman, Won‐Kyung Cho, Chung K. Chu et al. · Journal of Virology · 2011 · 285 citations · Full text

, , +17

1–5 of 131

Authors

816

  1. SP
    Stephen P. Goff

    Columbia University, United States

    8 publications · 782 citations

    8

    h-index

  2. MC
    Matthew C. Lorincz

    University of British Columbia, Canada

    8 publications · 1.6K citations

    8

    h-index

  3. JK
    Jonathan Karn

    Case Western Reserve University, United States

    7 publications · 962 citations

    7

    h-index

  4. AB
    Arsène Burny

    Université Libre de Bruxelles, Belgium

    6 publications · 361 citations

    6

    h-index

  5. YC
    Y. Cleuter

    Université Libre de Bruxelles, Belgium

    4 publications · 224 citations

    4

    h-index

1–5 of 816

Institutions

299

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    17 publications

    1.8K citations

  2. Columbia University

    New York, United States

    8 h-index

    21 publications

    2K citations

  3. Case Western Reserve University

    Cleveland, United States

    7 h-index

    33 publications

    4.5K citations

  4. University of British Columbia

    Vancouver, Canada

    7 h-index

    28 publications

    4.8K citations

  5. Inserm

    Paris, France

    7 h-index

    40 publications

    3.3K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    30 publications

    1.3K citations

  7. Czech Academy of Sciences, Institute of Molecular Genetics

    Prague, Czechia

    5 h-index

    11 publications

    789 citations

  8. Université Claude Bernard Lyon 1

    Villeurbanne, France

    4 h-index

    26 publications

    1.3K citations

1–8 of 299

Venues

  1. Journal of Virology

    JVI · 19 publications · 1.4K citations

    18

    h-index

  2. Retrovirology

    10 publications · 651 citations

    10

    h-index

  3. PLoS Pathogens

    8 publications · 552 citations

    8

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 928 citations

    8

    h-index

  5. Molecular and Cellular Biology

    MCB · 6 publications · 635 citations

    6

    h-index

1–5