Concepedia

Protocell Construction

Protocell Construction is a methodological framework in synthetic biology that enables the design and assembly of minimal, cell-like systems capable of essential life processes through the integration of a minimal genome with a lipid-based compartment, distinguishing it from other genome engineering approaches by its focus on generating functional, self-sustaining non-living entities that recapitulate basic cellular behaviors.

123

Publications

11.4K

Citations

413

Authors

193

Institutions

Publications per year

2017–2026

71

Parents

Publications

123

Man-made cell-like compartments for molecular evolution

Dan S. Tawfik, Andrew D. Griffiths · Nature Biotechnology · 1998 · 943 citations

, , +11

Template-directed synthesis of a genetic polymer in a model protocell

Sheref S. Mansy, Jason Schrum, Mathangi Krishnamurthy et al. · Nature · 2008 · 715 citations · Full text

, , +15

Peptide–nucleotide microdroplets as a step towards a membrane-free protocell model

Shogo Koga, David Williams, Adam W. Perriman et al. · Nature Chemistry · 2011 · 674 citations

, , +13

A scalable pipeline for designing reconfigurable organisms

Sam Kriegman, Douglas Blackiston, Michael Levin et al. · Proceedings of the National Academy of Sciences · 2020 · 471 citations · Full text

, , +6

Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model

T.‐Y. Dora Tang, Cik Rohaida Che Hak, Alex J. Thompson et al. · Nature Chemistry · 2014 · 438 citations · Full text

, , +14

1–5 of 123

Authors

413

  1. SM
    Stephen Mann

    University of Bristol, United Kingdom

    22 publications · 3.3K citations

    21

    h-index

  2. ML
    Mei Li

    University of Bristol, United Kingdom

    13 publications · 1.1K citations

    13

    h-index

  3. PS
    Pasquale Stano

    Roma Tre University, Italy

    8 publications · 577 citations

    8

    h-index

  4. YQ
    Yan Qiao

    Beijing National Laboratory for Molecular Sciences, China

    6 publications · 385 citations

    6

    h-index

  5. XH
    Xin Huang

    Harbin Institute of Technology, China

    5 publications · 223 citations

    5

    h-index

1–5 of 413

Institutions

193

  1. University of Bristol

    Bristol, United Kingdom

    22 h-index

    81 publications

    11.9K citations

  2. Shanghai Jiao Tong University

    Shanghai, China

    9 h-index

    22 publications

    1.1K citations

  3. Max Planck-Bristol Centre for Minimal Biology

    Bristol, United Kingdom

    9 h-index

    13 publications

    671 citations

  4. Radboud University Nijmegen

    Nijmegen, The Netherlands

    8 h-index

    24 publications

    2.4K citations

  5. Beijing National Laboratory for Molecular Sciences

    Beijing, China

    8 h-index

    26 publications

    1.4K citations

  6. Chinese Academy of Sciences

    Beijing, China

    8 h-index

    22 publications

    1.5K citations

  7. University of Chinese Academy of Sciences

    Beijing, China

    8 h-index

    25 publications

    2.5K citations

  8. Harbin Institute of Technology

    Harbin, China

    6 h-index

    35 publications

    2.1K citations

1–8 of 193

Venues

  1. Journal of the American Chemical Society

    JACS · 7 publications · 470 citations

    7

    h-index

  2. Origins of Life and Evolution of Biospheres

    7 publications · 448 citations

    7

    h-index

  3. Nature

    6 publications · 1.1K citations

    6

    h-index

  4. Nature Communications

    5 publications · 380 citations

    5

    h-index

  5. Angewandte Chemie International Edition

    5 publications · 423 citations

    5

    h-index

1–5