Concepedia

Proteolytic Invasion

Proteolytic Invasion is a pathological process in which tumor cells degrade the extracellular matrix and basement membrane through the localized secretion of proteolytic enzymes, thereby enabling invasion into surrounding tissues.

153

Publications

10.1K

Citations

809

Authors

298

Institutions

Publications per year

2017–2026

14

Parents

Publications

153

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

Paolo Mignatti, E. Robbins, Daniel B. Rifkin · Cell · 1986 · 750 citations

, , +16

High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis.

J Grøndahl-Hansen, I. J. Christensen, Christian Rosenquist et al. · PubMed · 1993 · 390 citations

, , +13

Tumor Cell Invasion Inhibited by TIMP-2

Adriana Albini, A Melchiori, L. Santi et al. · JNCI Journal of the National Cancer Institute · 1991 · 322 citations

, , +16

ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis

Xin Lü, Qiongqing Wang, Guohong Hu et al. · Genes & Development · 2009 · 303 citations · Full text

, , +17

N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors

Bojana Gligorijevic, Jeffrey Wyckoff, Hideki Yamaguchi et al. · Journal of Cell Science · 2012 · 268 citations · Full text

, , +17

1–5 of 153

Authors

809

  1. WG
    William G. Stetler‐Stevenson

    National Cancer Institute, United States

    5 publications · 756 citations

    5

    h-index

  2. AY
    Alex Y. Strongin

    Sanford Burnham Prebys Medical Discovery Institute, United States

    4 publications · 248 citations

    4

    h-index

  3. MC
    Mary C. Farach‐Carson

    University of Delaware, United States

    3 publications · 140 citations

    3

    h-index

  4. CF
    Claudio Festuccia

    University of L'Aquila, Italy

    3 publications · 110 citations

    3

    h-index

  5. DV
    Dmitri V. Rozanov

    Sanford Burnham Prebys Medical Discovery Institute, United States

    3 publications · 206 citations

    3

    h-index

1–5 of 809

Institutions

298

  1. University of Michigan

    Ann Arbor, United States

    5 h-index

    19 publications

    2.4K citations

  2. University of L'Aquila

    L’Aquila, Italy

    4 h-index

    12 publications

    385 citations

  3. The University of Osaka

    Osaka, Japan

    4 h-index

    9 publications

    243 citations

  4. Sanford Burnham Prebys Medical Discovery Institute

    La Jolla, United States

    4 h-index

    11 publications

    593 citations

  5. Wayne State University

    Detroit, United States

    4 h-index

    5 publications

    377 citations

  6. Rigshospitalet

    Copenhagen, Denmark

    3 h-index

    10 publications

    1.2K citations

  7. Inserm

    Paris, France

    3 h-index

    20 publications

    1.2K citations

  8. Cancer Research Center

    Columbia, United States

    3 h-index

    7 publications

    411 citations

1–8 of 298

Venues

  1. PubMed

    Repository · 20 publications · 1.9K citations

    16

    h-index

  2. Journal of Biological Chemistry

    JBC · 9 publications · 643 citations

    9

    h-index

  3. International Journal of Cancer

    7 publications · 380 citations

    7

    h-index

  4. Oncotarget

    5 publications · 150 citations

    5

    h-index

  5. International Journal of Oncology

    4 publications · 137 citations

    4

    h-index

1–5