Concepedia

Proteoglycan Depletion

Proteoglycan Depletion is a pathological process characterized by the reduction of proteoglycans in articular cartilage, distinguished from other forms of matrix degradation by its specific impact on the osmotic and load-bearing properties essential for joint integrity.

212

Publications

14.3K

Citations

938

Authors

313

Institutions

Publications per year

2017–2026

25

Parents

Publications

212

MicroRNA-140 plays dual roles in both cartilage development and homeostasis

Shigeru Miyaki, Tempei Sato, Atsushi Inoue et al. · Genes & Development · 2010 · 671 citations · Full text

, , +16

Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis

Sanshiro Hashimoto, Robert Ochs, Setsuro Komiya et al. · Arthritis & Rheumatism · 1998 · 504 citations

, , +17

Proteoglycan‐induced changes in <i>T</i><sub>1ρ</sub>‐relaxation of articular cartilage at 4T

Sarma V.S. Akella, Ravinder R. Regatte, Alexander J. Gougoutas et al. · Magnetic Resonance in Medicine · 2001 · 380 citations · Full text

, , +16

Fibril reinforced poroelastic model predicts specifically mechanical behavior of normal, proteoglycan depleted and collagen degraded articular cartilage

Rami K. Korhonen, Mikko S. Laasanen, Juha Töyräs et al. · Journal of Biomechanics · 2003 · 281 citations

, , +16

Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cytokines

Jenny A. Tyler · Biochemical Journal · 1989 · 277 citations · Full text

, , +16

1–5 of 212

Authors

938

  1. WB
    Wim B. van den Berg

    Radboud University Nijmegen, Netherlands

    10 publications · 573 citations

    10

    h-index

  2. RR
    Ravinder Reddy

    University of Pennsylvania, United States

    8 publications · 1.3K citations

    8

    h-index

  3. IK
    Ilkka Kiviranta

    University of Eastern Finland, Finland

    8 publications · 685 citations

    8

    h-index

  4. JS
    Jukka S. Jurvelin

    University of Eastern Finland, Finland

    8 publications · 948 citations

    8

    h-index

  5. JB
    J. Bruce Kneeland

    University of Pennsylvania, United States

    7 publications · 1.3K citations

    7

    h-index

1–5 of 938

Institutions

313

  1. Rush University Medical Center

    Chicago, United States

    18 h-index

    50 publications

    3.2K citations

  2. University of Eastern Finland

    Joensuu, Finland

    13 h-index

    61 publications

    5.2K citations

  3. Radboud University Nijmegen

    Nijmegen, The Netherlands

    12 h-index

    60 publications

    3.3K citations

  4. University of Pennsylvania

    Philadelphia, United States

    9 h-index

    47 publications

    8.3K citations

  5. Kuopio University Hospital

    Kuopio, Finland

    7 h-index

    26 publications

    2.4K citations

  6. Presbyterian St. Luke's Medical Center

    Denver, United States

    7 h-index

    20 publications

    1.4K citations

  7. Monash University

    Melbourne, Australia

    5 h-index

    18 publications

    533 citations

  8. Wellcome Trust

    London, United Kingdom

    4 h-index

    13 publications

    668 citations

1–8 of 313

Venues

  1. Arthritis & Rheumatism

    25 publications · 2.6K citations

    23

    h-index

  2. Journal of Orthopaedic Research®

    17 publications · 1K citations

    16

    h-index

  3. Annals of the Rheumatic Diseases

    ARD · 14 publications · 1K citations

    14

    h-index

  4. PubMed

    Repository · 12 publications · 459 citations

    11

    h-index

  5. Osteoarthritis and Cartilage

    9 publications · 499 citations

    9

    h-index

1–5