Concepedia

Protein-based Targeting

Protein-Based Targeting is a targeting strategy within active drug delivery systems that utilizes proteins or protein-derived molecules as ligands to selectively bind to specific cellular receptors, thereby enabling precise spatial and functional delivery of therapeutic agents.

131

Publications

6K

Citations

871

Authors

267

Institutions

Publications per year

2017–2026

46

Parents

Publications

131

Programmable protein delivery with a bacterial contractile injection system

Joseph Kreitz, Mirco Friedrich, Akash Guru et al. · Nature · 2023 · 222 citations · Full text

, , +13

Effector Cell Recruitment with Novel Fv-based Dual-affinity Re-targeting Protein Leads to Potent Tumor Cytolysis and in Vivo B-cell Depletion

Syd Johnson, Stephen Burke, Ling Huang et al. · Journal of Molecular Biology · 2010 · 192 citations

, , +15

Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases

Vishnu Raman, Nele Van Dessel, Christopher L. Hall et al. · Nature Communications · 2021 · 173 citations · Full text

, , +16

Bispecific Aptamer Induced Artificial Protein-Pairing: A Strategy for Selective Inhibition of Receptor Function

Liping Wang, Hong Liang, Jin Sun et al. · Journal of the American Chemical Society · 2019 · 155 citations

, , +14

A specific drug targeting system based on polyhydroxyalkanoate granule binding protein PhaP fused with targeted cell ligands

Yongchao Yao, Xiao-Yong Zhan, Jing Zhang et al. · Biomaterials · 2008 · 151 citations

, , +16

1–5 of 131

Authors

871

  1. FM
    Frits Moolenaar

    University of Groningen, Netherlands

    6 publications · 220 citations

    6

    h-index

  2. DD
    Dick de Zeeuw

    University of Groningen, Netherlands

    5 publications · 203 citations

    5

    h-index

  3. ZZ
    Zhiyuan Zhong

    Soochow University, China

    4 publications · 241 citations

    4

    h-index

  4. EJ
    Eric J. F. Franssen

    OLVG, Netherlands

    4 publications · 170 citations

    4

    h-index

  5. FM
    Fenghua Meng

    Soochow University, China

    4 publications · 241 citations

    4

    h-index

1–5 of 871

Institutions

267

  1. Massachusetts Institute of Technology

    Cambridge, United States

    7 h-index

    36 publications

    2.4K citations

  2. University of Groningen

    Groningen, The Netherlands

    7 h-index

    23 publications

    966 citations

  3. University of Maryland, Baltimore

    Baltimore, United States

    4 h-index

    9 publications

    331 citations

  4. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    15 publications

    1.1K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    17 publications

    2.4K citations

  6. Soochow University

    Suzhou, China

    4 h-index

    24 publications

    1.4K citations

  7. Southwest University

    Chongqing, China

    3 h-index

    15 publications

    575 citations

  8. Heidelberg University

    Heidelberg, Germany

    3 h-index

    5 publications

    410 citations

1–8 of 267

Venues

  1. Journal of the American Chemical Society

    JACS · 7 publications · 428 citations

    7

    h-index

  2. Biomaterials

    6 publications · 419 citations

    6

    h-index

  3. Bioconjugate Chemistry

    5 publications · 108 citations

    5

    h-index

  4. Journal of Controlled Release

    5 publications · 189 citations

    5

    h-index

  5. Angewandte Chemie International Edition

    4 publications · 177 citations

    4

    h-index

1–5