Concepedia

Protein Folding Optimization

Protein Folding Optimization is a computational or experimental methodology within protein engineering that specifically enhances the efficiency, accuracy, and stability of a protein's three-dimensional conformational assembly by systematically refining sequence, environmental, or structural determinants to achieve a desired functional fold.

159

Publications

9.5K

Citations

481

Authors

192

Institutions

Publications per year

2017–2026

14

Parents

Publications

159

Engineering of stable and fast-folding sequences of model proteins.

Eugene I. Shakhnovich, A. M. Gutin · Proceedings of the National Academy of Sciences · 1993 · 539 citations

, , +16

Optimal protein-folding codes from spin-glass theory.

Richard A. Goldstein, Zaida Luthey‐Schulten, Peter G. Wolynes · Proceedings of the National Academy of Sciences · 1992 · 349 citations

, , +14

A Large Scale Test of Computational Protein Design: Folding and Stability of Nine Completely Redesigned Globular Proteins

Gautam Dantas, Brian Kuhlman, David R. Callender et al. · Journal of Molecular Biology · 2003 · 318 citations

, , +14

A test of lattice protein folding algorithms.

Kaizhi Yue, Klaus M. Fiebig, Paul D. Thomas et al. · Proceedings of the National Academy of Sciences · 1995 · 293 citations

, , +17

Proteolytic selection for protein folding using filamentous bacteriophages

Peter Kristensen, Greg Winter · Folding and Design · 1998 · 265 citations

, , +14

1–5 of 159

Authors

481

  1. DB
    David Baker

    University of Washington, United States

    4 publications · 712 citations

    4

    h-index

  2. RE
    Ron Elber

    The University of Texas at Austin, United States

    4 publications · 254 citations

    4

    h-index

  3. HS
    Heitor Silvério Lopes

    Universidade Tecnológica Federal do Paraná, Brazil

    4 publications · 63 citations

    4

    h-index

  4. BK
    Brian Kuhlman

    University of North Carolina at Chapel Hill, United States

    3 publications · 665 citations

    3

    h-index

  5. LW
    Lenan Wu

    Southeast University, China

    3 publications · 80 citations

    3

    h-index

1–5 of 481

Institutions

192

  1. Cornell University

    Ithaca, United States

    10 h-index

    19 publications

    1.3K citations

  2. University of Washington

    Seattle, United States

    7 h-index

    24 publications

    3.8K citations

  3. Johns Hopkins University

    Baltimore, United States

    5 h-index

    11 publications

    646 citations

  4. Universidade Tecnológica Federal do Paraná

    Curitiba, Brazil

    4 h-index

    7 publications

    113 citations

  5. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    8 publications

    404 citations

  6. Harvard University

    Cambridge, United States

    3 h-index

    7 publications

    1.4K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    6 publications

    1.1K citations

  8. Indian Institute of Technology Delhi

    New Delhi, India

    3 h-index

    9 publications

    389 citations

1–8 of 192

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 1.9K citations

    12

    h-index

  2. Journal of Molecular Biology

    JMB · 8 publications · 866 citations

    8

    h-index

  3. Protein Science

    PS · 5 publications · 268 citations

    5

    h-index

  4. Proteins Structure Function and Bioinformatics

    4 publications · 319 citations

    4

    h-index

  5. Computational Biology and Chemistry

    CBAC · 4 publications · 97 citations

    4

    h-index

1–5