Concepedia

Protein Binding Selectivity

Protein Binding Selectivity is a molecular recognition phenomenon characterized by the preferential interaction of a ligand with specific protein targets over others, distinguished by the structural and physicochemical complementarity that governs binding affinity and specificity within a biological system.

196

Publications

11.2K

Citations

1K

Authors

332

Institutions

Publications per year

2017–2026

48

Variants

Protein Binding Specificity

Parents

Publications

196

PDZ Domain Binding Selectivity Is Optimized Across the Mouse Proteome

Michael A. Stiffler, Jiunn R Chen, Viara Grantcharova et al. · Science · 2007 · 381 citations · Full text

, , +17

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

Paul A. Clemons, Nicole E. Bodycombe, Hyman A. Carrinski et al. · Proceedings of the National Academy of Sciences · 2010 · 352 citations · Full text

, , +17

The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51

Aura Carreira, Jovencio Hilario, Ichiro Amitani et al. · Cell · 2009 · 257 citations · Full text

, , +12

Nonstatistical binding of a protein to clustered carbohydrates

Nina Horan, Lin Yan, Hiroyuki Isobe et al. · Proceedings of the National Academy of Sciences · 1999 · 201 citations

, , +17

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization

Joseph N. McLaughlin, Myla M. Patterson, Asrar B. Malik · Proceedings of the National Academy of Sciences · 2007 · 175 citations · Full text

, , +14

1–5 of 196

Authors

1K

  1. HW
    Harel Weinstein

    Cornell University, United States

    3 publications · 193 citations

    3

    h-index

  2. JW
    Jeffery W. Kelly

    Scripps Research Institute, United States

    3 publications · 291 citations

    3

    h-index

  3. AB
    Anna Barnard

    University of York, United Kingdom

    2 publications · 120 citations

    2

    h-index

  4. DL
    Dann L. Parker

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    2 publications · 127 citations

    2

    h-index

  5. AS
    Ayaka Suenaga

    Kumamoto University, Japan

    2 publications · 106 citations

    2

    h-index

1–5 of 1K

Institutions

332

  1. National Institutes of Health

    Bethesda, United States

    8 h-index

    22 publications

    1.9K citations

  2. Monash University

    Melbourne, Australia

    6 h-index

    34 publications

    1.9K citations

  3. Washington University in St. Louis

    St Louis, United States

    5 h-index

    25 publications

    2.8K citations

  4. Scripps Research Institute

    San Diego, United States

    5 h-index

    19 publications

    1.3K citations

  5. Rensselaer Polytechnic Institute

    Troy, United States

    4 h-index

    19 publications

    967 citations

  6. Philipps University of Marburg

    Marburg, Germany

    4 h-index

    17 publications

    513 citations

  7. Harvard University

    Cambridge, United States

    4 h-index

    17 publications

    4.5K citations

  8. Icahn School of Medicine at Mount Sinai

    New York, United States

    4 h-index

    14 publications

    827 citations

1–8 of 332

Venues

  1. Journal of Biological Chemistry

    JBC · 22 publications · 2K citations

    21

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 1.4K citations

    12

    h-index

  3. Journal of the American Chemical Society

    JACS · 10 publications · 596 citations

    9

    h-index

  4. Journal of Medicinal Chemistry

    9 publications · 344 citations

    9

    h-index

  5. Biochemistry

    8 publications · 309 citations

    8

    h-index

1–5