Concepedia

Proofreading Mechanisms

Proofreading Mechanisms is a biochemical process in molecular biology that ensures the fidelity of nucleic acid replication by selectively identifying and correcting mismatched nucleotides during genome synthesis in both microbial and viral systems.

231

Publications

16.9K

Citations

751

Authors

299

Institutions

Publications per year

2017–2026

51

Parents

Publications

231

Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

J. J. Hopfield · Proceedings of the National Academy of Sciences · 1974 · 1.6K citations · Full text

, , +14

The Accuracy of Reverse Transcriptase from HIV-1

John D. Roberts, Katarzyna Bębenek, Thomas A. Kunkel · Science · 1988 · 980 citations

, , +17

Structural basis and functional analysis of the SARS coronavirus nsp14–nsp10 complex

Yuanyuan Ma, Lijie Wu, Neil Shaw et al. · Proceedings of the National Academy of Sciences · 2015 · 550 citations · Full text

, , +17

Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase

David A. Steinhauer, Esteban Domingo, John J. Holland · Gene · 1992 · 415 citations

, , +12

Proofreading and Aminoacylation of tRNAs Before Export from the Nucleus

Elsebet Lund, James E. Dahlberg · Science · 1998 · 314 citations

, , +17

1–5 of 231

Authors

751

  1. TA
    Thomas A. Kunkel

    National Institute of Environmental Health Sciences, United States

    21 publications · 2.9K citations

    21

    h-index

  2. LJ
    Linda J. Reha-Krantz

    University of Alberta, Canada

    8 publications · 395 citations

    8

    h-index

  3. RM
    Roel M. Schaaper

    National Institute of Environmental Health Sciences, United States

    8 publications · 685 citations

    8

    h-index

  4. FV
    Friedrich von der Haar

    Max Planck Institute of Experimental Medicine, Germany

    7 publications · 358 citations

    7

    h-index

  5. MF
    Myron F. Goodman

    University of Southern California, United States

    6 publications · 570 citations

    6

    h-index

1–5 of 751

Institutions

299

  1. National Institute of Environmental Health Sciences

    Durham, United States

    25 h-index

    76 publications

    9.5K citations

  2. National Institutes of Health

    Bethesda, United States

    13 h-index

    35 publications

    3.1K citations

  3. University of Washington

    Seattle, United States

    12 h-index

    43 publications

    4.1K citations

  4. University of Alberta

    Edmonton, Canada

    8 h-index

    25 publications

    1.3K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    18 publications

    1K citations

  6. Rockefeller University

    New York, United States

    7 h-index

    13 publications

    1K citations

  7. University of Southern California

    Los Angeles, United States

    7 h-index

    20 publications

    1.4K citations

  8. Max Planck Institute of Experimental Medicine

    Göttingen, Germany

    6 h-index

    19 publications

    635 citations

1–8 of 299

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 35 publications · 5.1K citations

    32

    h-index

  2. Journal of Biological Chemistry

    JBC · 32 publications · 2.5K citations

    25

    h-index

  3. Nucleic Acids Research

    16 publications · 516 citations

    15

    h-index

  4. Biochemistry

    14 publications · 811 citations

    14

    h-index

  5. Journal of Bacteriology

    JB · 6 publications · 282 citations

    6

    h-index

1–5