Concepedia

Pronuclear Transfer

Pronuclear Transfer is a micromanipulation technique in embryo engineering wherein the pronuclei from a zygote with pathogenic mitochondrial DNA mutations are transferred into an enucleated donor zygote with healthy mitochondria, thereby preventing mitochondrial disease transmission.

92

Publications

7K

Citations

412

Authors

150

Institutions

Publications per year

2017–2026

13

Variants

Pronuclear Transplantation

Parents

Publications

92

Nuclear Transplantation in the Mouse Embryo by Microsurgery and Cell Fusion

James McGrath, Davor Solter · Science · 1983 · 586 citations

, , +13

Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease

Lyndsey Craven, Helen Tuppen, Gareth D. Greggains et al. · Nature · 2010 · 480 citations · Full text

, , +10

Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA

Daisuke Mashiko, Yoshitaka Fujihara, Yuhkoh Satouh et al. · Scientific Reports · 2013 · 434 citations · Full text

, , +17

The successful use of pronuclear embryo transfers the day following oocyte retrieval

Laurie Scott, Samuel Smith · Human Reproduction · 1998 · 396 citations

, , +17

Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease

Louise Hyslop, Paul Blakeley, Lyndsey Craven et al. · Nature · 2016 · 351 citations · Full text

, , +13

1–5 of 92

Authors

412

  1. DS
    Davor Solter

    The Wistar Institute, United States

    4 publications · 920 citations

    4

    h-index

  2. KE
    Keith E. Latham

    Temple University, United States

    4 publications · 105 citations

    4

    h-index

  3. JL
    John L. Yovich

    Mount Medical Centre, Australia

    4 publications · 234 citations

    3

    h-index

  4. YT
    Y. Tsunoda

    Kindai University, Japan

    3 publications · 160 citations

    3

    h-index

  5. BH
    Björn Heindryckx

    Ghent University Hospital, Belgium

    3 publications · 85 citations

    3

    h-index

1–5 of 412

Institutions

150

  1. Temple University

    Philadelphia, United States

    5 h-index

    23 publications

    633 citations

  2. Newcastle University

    Newcastle upon Tyne, United Kingdom

    3 h-index

    6 publications

    1.6K citations

  3. University of Tsukuba

    Tsukuba, Japan

    3 h-index

    8 publications

    144 citations

  4. The University of Western Australia

    Perth, Australia

    3 h-index

    11 publications

    966 citations

  5. Ghent University Hospital

    Ghent, Belgium

    3 h-index

    26 publications

    753 citations

  6. The Wistar Institute

    Philadelphia, United States

    3 h-index

    6 publications

    1.5K citations

  7. Obihiro University of Agriculture and Veterinary Medicine

    Obihiro, Japan

    3 h-index

    9 publications

    261 citations

  8. Mount Medical Centre

    Wantirna, Australia

    3 h-index

    13 publications

    888 citations

1–8 of 150

Venues

  1. Human Reproduction

    7 publications · 630 citations

    7

    h-index

  2. Biology of Reproduction

    7 publications · 535 citations

    7

    h-index

  3. PubMed

    Repository · 5 publications · 126 citations

    5

    h-index

  4. Transgenic Research

    4 publications · 149 citations

    4

    h-index

  5. Development

    4 publications · 310 citations

    4

    h-index

1–5