Concepedia

Pronuclear Microinjection

Pronuclear Microinjection is a genetic engineering technique in which foreign DNA is directly introduced into the pronucleus of a fertilized oocyte to generate transgenic animal models.

135

Publications

11.4K

Citations

668

Authors

222

Institutions

Publications per year

2017–2026

14

Parents

Children

Publications

135

Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.

Ralph L. Brinster, H Y Chen, Myrna E. Trumbauer et al. · Proceedings of the National Academy of Sciences · 1985 · 1.1K citations · Full text

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Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts

Angelika Schnieke, Alexander Kind, William A. Ritchie et al. · Science · 1997 · 905 citations

, , +17

Integration and Stable Germ Line Transmission of Genes Injected into Mouse Pronuclei

Jon W. Gordon, Frank H. Ruddle · Science · 1981 · 685 citations

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FVB/N: an inbred mouse strain preferable for transgenic analyses.

Makoto M. Taketo, Allen C. Schroeder, L E Mobraaten et al. · Proceedings of the National Academy of Sciences · 1991 · 610 citations · Full text

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Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease

Lyndsey Craven, Helen Tuppen, Gareth D. Greggains et al. · Nature · 2010 · 480 citations · Full text

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1–5 of 135

Authors

668

  1. MO
    Masato Ohtsuka

    Tokai University, Japan

    7 publications · 223 citations

    7

    h-index

  2. RY
    Ryuzo Yanagimachi

    University of Hawaii System, United States

    6 publications · 556 citations

    6

    h-index

  3. MS
    Masahiro Sato

    Kagoshima University, Japan

    5 publications · 164 citations

    5

    h-index

  4. LM
    Lluı́s Montoliu

    Centro Nacional de Biotecnología, Spain

    4 publications · 240 citations

    4

    h-index

  5. TR
    Thomas Rülicke

    University of Veterinary Medicine Vienna, Austria

    4 publications · 210 citations

    4

    h-index

1–5 of 668

Institutions

222

  1. The University of Tokyo

    Tokyo, Japan

    8 h-index

    21 publications

    1K citations

  2. Tokai University

    Tokyo, Japan

    8 h-index

    18 publications

    556 citations

  3. Kagoshima University

    Kagoshima, Japan

    6 h-index

    20 publications

    1K citations

  4. University of Hawaii System

    Honolulu, United States

    5 h-index

    16 publications

    1.2K citations

  5. University of Zurich

    Zurich, Switzerland

    4 h-index

    5 publications

    204 citations

  6. Baylor College of Medicine

    Houston, United States

    4 h-index

    13 publications

    247 citations

  7. The University of Osaka

    Osaka, Japan

    4 h-index

    7 publications

    253 citations

  8. University of Nebraska Medical Center

    Omaha, United States

    4 h-index

    7 publications

    228 citations

1–8 of 222

Venues

  1. Theriogenology

    10 publications · 274 citations

    10

    h-index

  2. Molecular Reproduction and Development

    9 publications · 324 citations

    9

    h-index

  3. Transgenic Research

    7 publications · 246 citations

    7

    h-index

  4. PubMed

    Repository · 6 publications · 151 citations

    6

    h-index

  5. Methods in molecular biology

    Book series · 6 publications · 105 citations

    6

    h-index

1–5