Concepedia

Promoter Optimization

Promoter Optimization is a methodological approach in synthetic biology that systematically refines promoter sequences to enhance transcriptional efficiency, specificity, or regulatability by altering regulatory elements, architecture, or sequence composition.

95

Publications

5.6K

Citations

458

Authors

144

Institutions

Publications per year

2017–2026

45

Parents

Publications

95

Programming gene expression with combinatorial promoters

Robert Sidney Cox, Michael G. Surette, Michael B. Elowitz · Molecular Systems Biology · 2007 · 381 citations · Full text

, , +14

Use of the human elongation factor 1α promoter as a versatile and efficient expression system

Dong Wan Kim, Taichi Uetsuki, Yoshito Kaziro et al. · Gene · 1990 · 285 citations

, , +12

Genome-scale promoter engineering by coselection MAGE

Harris H. Wang, Hwangbeom Kim, Le Cong et al. · Nature Methods · 2012 · 236 citations · Full text

, , +14

Synthetic promoter designs enabled by a comprehensive analysis of plant core promoters

Tobias Jores, Jackson Tonnies, Travis Wrightsman et al. · Nature Plants · 2021 · 217 citations · Full text

, , +16

Upstream elements necessary for optimal function of the hsp 70 promoter in transformed flies

Robert Dudler, Andrew Travers · Cell · 1984 · 213 citations

, , +13

1–5 of 95

Authors

458

  1. JC
    Jian Chen

    Jiangnan University, China

    3 publications · 309 citations

    3

    h-index

  2. AD
    Andrew D. Ellington

    The University of Texas at Austin, United States

    3 publications · 86 citations

    3

    h-index

  3. JZ
    Jingwen Zhou

    Jiangnan University, China

    3 publications · 206 citations

    3

    h-index

  4. ES
    Edward S. Buckler

    Cornell University, United States

    2 publications · 229 citations

    2

    h-index

  5. HS
    Hal S. Alper

    The University of Texas at Austin, United States

    2 publications · 183 citations

    2

    h-index

1–5 of 458

Institutions

144

  1. Jiangnan University

    Wuxi, China

    8 h-index

    45 publications

    2.2K citations

  2. The University of Texas at Austin

    Austin, United States

    5 h-index

    20 publications

    1.2K citations

  3. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    15 publications

    716 citations

  4. Korea Advanced Institute of Science and Technology

    Daejeon, South Korea

    3 h-index

    10 publications

    154 citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    6 publications

    746 citations

  6. Tsinghua University

    Beijing, China

    3 h-index

    18 publications

    1.5K citations

  7. University of Calgary

    Calgary, Canada

    2 h-index

    2 publications

    399 citations

  8. Agricultural Research Service

    Washington, United States

    2 h-index

    2 publications

    229 citations

1–8 of 144

Venues

  1. Applied Microbiology and Biotechnology

    9 publications · 534 citations

    9

    h-index

  2. Journal of Biotechnology

    7 publications · 294 citations

    7

    h-index

  3. Biotechnology and Bioengineering

    5 publications · 298 citations

    5

    h-index

  4. ACS Synthetic Biology

    4 publications · 163 citations

    4

    h-index

  5. Nucleic Acids Research

    4 publications · 475 citations

    4

    h-index

1–5