Concepedia

Prohormone Structure

Prohormone Structure is a biochemical precursor molecule that belongs to the class of polypeptide or protein-based hormonal intermediates, distinguished by its requirement for enzymatic modification to yield an active hormone.

132

Publications

7.4K

Citations

515

Authors

187

Institutions

Publications per year

2017–2026

2

Parents

Publications

132

Cloning and Primary Sequence of a Mouse Candidate Prohormone Convertase PC1 Homologous to PC2, Furin, and Kex2: Distinct Chromosomal Localization and Messenger RNA Distribution in Brain and Pituitary Compared to PC2

Nabil G. Seidah, M. Marcinkiewicz, Suzanne Benjannet et al. · Molecular Endocrinology · 1991 · 480 citations · Full text

, , +15

Human Relaxin Gene 3 (H3) and the Equivalent Mouse Relaxin (M3) Gene

Ross A. D. Bathgate, Chrishan S. Samuel, T.C.D. Burazin et al. · Journal of Biological Chemistry · 2002 · 378 citations · Full text

, , +8

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes.

Laurel Thomas, Richard Leduc, Barbara A. Thorne et al. · Proceedings of the National Academy of Sciences · 1991 · 320 citations

, , +17

An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing.

Tokio Sanke, Graeme I. Bell, Clare E. Sample et al. · Journal of Biological Chemistry · 1988 · 258 citations · Full text

, , +17

Mammalian pancreatic preproglucagon contains three glucagon-related peptides.

Linda C. Lopez, Marsha L. Frazier, C J Su et al. · Proceedings of the National Academy of Sciences · 1983 · 230 citations · Full text

, , +15

1–5 of 132

Authors

515

  1. NG
    Nabil G. Seidah

    Montreal Clinical Research Institute, Canada

    6 publications · 714 citations

    6

    h-index

  2. IL
    Iris Lindberg

    University Medical Center New Orleans, United States

    6 publications · 248 citations

    6

    h-index

  3. DF
    Donald F. Steiner

    University of Chicago, United States

    5 publications · 679 citations

    5

    h-index

  4. WP
    Wijnand P. M. Geraerts

    Vrije Universiteit Amsterdam, Netherlands

    4 publications · 132 citations

    4

    h-index

  5. GT
    Gregg T. Nagle

    The University of Texas Medical Branch at Galveston, United States

    4 publications · 75 citations

    4

    h-index

1–5 of 515

Institutions

187

  1. Montreal Clinical Research Institute

    Montreal, Canada

    7 h-index

    28 publications

    5.1K citations

  2. Université de Montréal

    Montreal, Canada

    7 h-index

    27 publications

    1.3K citations

  3. Stanford University

    Stanford, United States

    6 h-index

    16 publications

    889 citations

  4. Massachusetts General Hospital

    Boston, United States

    5 h-index

    23 publications

    1K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    21 publications

    787 citations

  6. National Institutes of Health

    Bethesda, United States

    5 h-index

    19 publications

    1.6K citations

  7. University Medical Center New Orleans

    New Orleans, United States

    4 h-index

    10 publications

    458 citations

  8. Radboud University Nijmegen

    Nijmegen, The Netherlands

    4 h-index

    13 publications

    450 citations

1–8 of 187

Venues

  1. Journal of Biological Chemistry

    JBC · 24 publications · 1.9K citations

    18

    h-index

  2. Endocrinology

    14 publications · 578 citations

    13

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 1.2K citations

    12

    h-index

  4. FEBS Letters

    8 publications · 304 citations

    8

    h-index

  5. Biochemistry

    4 publications · 264 citations

    4

    h-index

1–5